Fungal Morphogenesis

Authors

Xiaorong Lin, Texas A&M University
J. Andrew Alspaugh, Duke University Medical Center
Haoping Liu, University of California, Irvine
Steven D. Harris, University of Nebraska-LincolnFollow

Date of this Version

2015

Citation

Cold Spring Harb Perspect Med 2015;5:a019679

Comments

Copyright 2015 Cold Spring Harbor Laboratory Press

Abstract

Morphogenesis in fungi is often induced by extracellular factors and executed by fungal genetic factors. Cell surface changes and alterations of the microenvironment often accompany morphogenetic changes in fungi. In this review, we will first discuss the general traits of yeast and hyphal morphotypes and how morphogenesis affects development and adaptation by fungi to their native niches, including host niches. Then we will focus on the molecular machinery responsible for the two most fundamental growth forms, yeast and hyphae. Last, we will describe how fungi incorporate exogenous environmental and host signals together with genetic factors to determine their morphotype and how morphogenesis, in turn, shapes the fungal microenvironment.