The 2008 Update of the Aspergillus nidulans Genome Annotation: A Community Effort

Authors

Jennifer Russo Wortman, Department of Medicine Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
Steven D. Harris, University of Nebraska-LincolnFollow
Geoffrey Turner, University of Sheffield, Sheffield, UKFollow
Aspergillus nidulans consortium

Document Type

Article

Date of this Version

2009

Comments

Published in Fungal Genetics and Biology 46 (2009) S2–S13.

Abstract

The identification and annotation of protein-coding genes is one of the primary goals of whole-genome sequencing projects, and the accuracy of predicting the primary protein products of gene expression is vital to the interpretation of the available data and the design of downstream functional applications. Nevertheless, the comprehensive annotation of eukaryotic genomes remains a considerable challenge. Many genomes submitted to public databases, including those of major model organisms, contain significant numbers of wrong and incomplete gene predictions. We present a community-based reannotation of the Aspergillus nidulans genome with the primary goal of increasing the number and quality of protein functional assignments through the careful review of experts in the field of fungal biology.