COMPOSITIONS AND COMPOUNDS FOR USE AS MOLECULAR ADJUVANT FOR A NCOTINE WACCNE

Authors

Sam D.G. Sanderson, Omaha, NE
Jonathan L. Vennerstrom, Omaha, NE
Geoffrey M. Thiele, Omaha, NE
Maniyan Parameswaran, Woburn, MA
Rick A. Bevins, Lincoln, NEFollow
Cheruku R. Srinivasa, Woburn, MA

Document Type

Article

Date of this Version

4-28-2005

Citation

United States Patent Application Publication Pub. No.: US 2005/0089524A1

Abstract

Compounds are disclosed comprising molecular adjuvants having an antigen presenting cell-targeting ligand linked to a nicotine hapten. Methods are disclosed for employing the compounds as a nicotine vaccine for treatment or prevention of nicotine addiction.