Patterned Alginate Hydrogels to Induce Chondrocyte Alignment

Authors

Jordan Catherine Verplank, University of Nebraska-LincolnFollow
Taylor D. Laughlin, University of Nebraska-LincolnFollow
Angela K. Pannier, University of Nebraska-LincolnFollow

Date of this Version

4-2016

Document Type

Poster

Citation

Poster, Spring 2016 Research Fair, University of Nebraska-Lincoln.

Comments

Copyright (c) 2016 Jordan Verplank, Taylor D. Laughlin, Angela K. Pannier

Abstract

The growth plate has an intricate architecture, and this architecture is necessary for directional growth of bones. Specifically, the cells align in longitudinal columns. As the growth plate expands with this pattern, the bone elongates with the same alignment pattern. The purpose of this research is to mimic this single celled, columnar alignment in vitro. In developing this alignment in vitro, this research will contribute to the overall study of growing growth for the development of improved therapeutic treatments and engineered tissues for transplants.