Bacterial Peritonitis Due to Acinetobacter baumannii Sequence Type 25 with Plasmid-Borne New Delhi Metallo-Beta-Lactamase in Honduras

Authors

Paige E. Waterman, Walter Reed Army Institute of Research
Patrick McGann, Walter Reed Army Institute of Research
Erik Snesrud, Walter Reed Army Institute of Research
Robert J. Clifford, Walter Reed Army Institute of Research
Yoon I. Kwak, Walter Reed Army Institute of Research
Ivon P. Munoz-Urbizo, Hospital Escuela
Juana Tabora-Castellanos, Hospital Escuela
Michael Milillo, Walter Reed Army Institute of Research
Lan Preston, Walter Reed Army Institute of Research
Ricardo Aviles, Joint Task Force-Bravo
Deena E. Sutter, San Antonio Military Medical Center
Emil P. Lesho, Walter Reed Army Institute of Research

Document Type

Article

Date of this Version

2013

Citation

Antimicrobial Agents and Chemotherapy, September 2013, Volume 57, Number 9, pp. 4584–4586. doi:10.1128/AAC.00275-13.

Comments

US government work.

Abstract

A carbapenem-resistant Acinetobacter baumannii strain was isolated from the peritoneal fluid of a patient with complicated intra-abdominal infection and evaluated at the Multidrug-resistant Organism Repository and Surveillance Network by wholegenome sequencing and real-time PCR. The isolate was sequence type 25 and susceptible to colistin and minocycline, with low MICs of tigecycline. bla_NDM-1 was located on a plasmid with >99% homology to pNDM-BJ02. The isolate carried numerous other antibiotic resistance genes, including the 16S methylase gene, armA.