U.S. Department of Agriculture: Agricultural Research Service, Lincoln, Nebraska
Date of this Version
5-22-2020
Citation
U.S. government works are not subject to copyright.
Abstract
Fusarium head blight (FHB), a fungal disease caused by Fusarium species that produce food toxins, currently devastates wheat production worldwide, yet few resistance resources have been discovered in wheat germplasm. Here, we cloned the FHB resistance gene Fhb7 by assembling the genome of Thinopyrum elongatum, a species used in wheat distant hybridization breeding. Fhb7 encodes a glutathione S-transferase (GST) and confers broad resistance to Fusarium species by detoxifying trichothecenes through de-epoxidation. Fhb7 GST homologs are absent in plants, and our evidence supports that Th. elongatum has gained Fhb7 through horizontal gene transfer (HGT) from an endophytic Epichloë species. Fhb7 introgressions in wheat confers resistance to both FHB and crown rot in diverse wheat backgrounds without yield penalty, providing a solution for Fusarium resistance breeding.
Wang SCIENCE 2020 data 1.xlsx (1103 kB)
Wang SCIENCE 2020 data 2.xlsx (11 kB)
Wang SCIENCE 2020 data 3.xlsx (448 kB)
Wang SCIENCE 2020 checklist.pdf (108 kB)
Comments
Wang et al., Science 368, eaba5435 (2020) 22 May 2020