U.S. Department of Agriculture: Agricultural Research Service, Lincoln, Nebraska
Date of this Version
11-2004
Citation
INFECTION AND IMMUNITY, 72(11): Nov. 2004, p. 6680–6684
Abstract
Shiga toxin (Stx) binding sites in porcine tissues and leukocytes were identified by the use of Stx overlay and anti-CD77/Gb3 immunoassays. Stx1 and Stx2 bound to similar tissue locations and leukocytes, although some differences were noted. Previously unreported Stx binding sites were identified in kidney tubules, intestinal lymphoid aggregates, sinusoidal liver cells, alveolar macrophages, and peripheral blood leukocytes.