Demographic Risk Factors for Severe and Fatal Vivax and Falciparum Malaria Among Hospital Admissions in Northeastern Indonesian Papua

Authors

Mazie J. Barcus
Hasan Basri, Family Health InternationalFollow
Helena Picarima, Family Health International
C. Manyakori, R.S. Persahabatan
Sekartuti, Puslitbang Biomedis & Farmasi
Iqbal Elyazar, U.S. Naval Medical Research Unit # 2Follow
Michael J. Bangs, Public Health and Malaria Control Department
Jason D. Maguire, Naval Medical CenterFollow
J. Kevin Baird, Eijkman InstituteFollow

Date of this Version

2007

Citation

Published in Am. J. Trop. Med. Hyg. (2007) 77(5), pp. 984–991

Abstract

Between January 1998 and December 2000, the Jayapura Provincial Public Hospital in northeastern Indonesian New Guinea (Papua) admitted 5,936 patients with a diagnosis of malaria. The microscopic diagnosis at admission was Plasmodium falciparum (3,976, 67%), Plasmodium vivax (1,135, 19%), Plasmodium malariae (8, < 1%), and mixed species infections (817, 14%). Approximately 9% (367) of patients were classified as having severe malaria (277 P. falciparum, 36 P. vivax, 53 mixed infections, and 1 P. malariae) and 88 died (79 P. falciparum/mixed infections and 9 P. vivax). Risk of fatal outcomes among severe malaria patients was indistinguishable between those with falciparum versus vivax malaria (OR=0.89; P=0.771). Compared with non-pregnant women, pregnant women showed no higher risk of severe malaria (P=0.643) or death caused by severe malaria (P=0.748). This study compares admissions per population (based on census data), parasitemia, morbidity, and mortality among children versus adults, pregnant versus non-pregnant women, and urban/suburban versus rural residents.