Enrofloxacin and Sulfamethoxazole Sorption on Carbonized Leonardite: Kinetics, Isotherms, Influential Effects, and Antibacterial Activity toward S. aureus ATCC 25923

Authors

Chanat Chokejaroenrat, Kasetsart University
Chainarong Sakulthaew, Kasetsart University
Khomson Satchasataporn, Kasetsart University
Daniel D. Snow, University of Nebraska-LincolnFollow
Tarik E. Ali, King Khalid University, Ain Shams University
Mohammed A. Assiri, King Khalid University
Apichon Watcharenwong, Suranaree University of Technology,
Saksit Imman, University of Phayao
Nopparat Suriyachai, University of Phayao
Torpong Kreetachat, University of Phayao

Document Type

Article

Date of this Version

9-16-2022

Citation

Chokejaroenrat, C.; Sakulthaew, C.; Satchasataporn, K.; Snow, D.D.; Ali, T.E.; Assiri, M.A.; Watcharenwong, A.; Imman, S.; Suriyachai, N.; Kreetachat, T. Enrofloxacin and Sulfamethoxazole Sorption on Carbonized Leonardite: Kinetics, Isotherms, Influential Effects, and Antibacterial Activity toward S. aureus ATCC 25923. Antibiotics 2022, 11, 1261. https://doi.org/10.3390/ antibiotics11091261

Comments

Open access.

Abstract

Excessive antibiotic use in veterinary applications has resulted in water contamination and potentially poses a serious threat to aquatic environments and human health. The objective of the current study was to quantify carbonized leonardite (cLND) adsorption capabilities to remove sulfamethoxazole (SMX)- and enrofloxacin (ENR)-contaminated water and to determine the microbial activity of ENR residuals on cLND following adsorption. The cLND samples prepared at 450^oC and 850^oC (cLND450 and cLND550, respectively) were evaluated for structural and physical characteristics and adsorption capabilities based on adsorption kinetics and isotherm studies. The low pyrolysis temperature of cLND resulted in a heterogeneous surface that was abundant in both hydrophobic and hydrophilic functional groups. SMX and ENR adsorption were best described using a pseudo-second-order rate expression. The SMX and ENR adsorption equilibrium data on cLND450 and cLND550 revealed their better compliance with a Langmuir isotherm than with four other models based on 2.3-fold higher values of q_mENR than q_mSMX. Under the presence of the environmental interference, the electrostatic interaction was the main contributing factor to the adsorption capability. Microbial activity experiments based on the growth of Staphylococcus aureus ATCC 25923 revealed that cLND could successfully adsorb and subsequently retain the adsorbed antibiotic on the cLND surface. This study demonstrated the potential of cLND550 as a suitable low-cost adsorbent for the highly efficient removal of antibiotics from water.