Genomic Differences between Preweaning Survival and Mortality of Piglets Following PEDV Outbreaks

Authors

Francesca Bertolini, University of Saskatchewan, Canada
John C.S. Harding, University of Saskatchewan, CanadaFollow
Benny Mote, University of Nebraska-LincolnFollow
Graham S. Plastow, University of Alberta
Max Rothschild, Iowa State UniversityFollow

Document Type

Article

Date of this Version

2016

Citation

Iowa State University Animal Industry Report 2016

Comments

Copyright 2016 Iowa State University of Science and Technology.

Abstract

Porcine Epidemic Diarrhea (PED) is a serious and potentially devastating disease in the US and Canadian pig industries. To investigate if there is genetic resistance to PEDV a total of 156 dead and 106 surviving neonatal piglets infected with PEDV were genotyped with over 60,000 genetic markers to investigate genetic differences between the two groups. This allows for the identification of genomic regions that could be linked to susceptibility/resistance to virus infection and in cellular components that are involved in the PED virus infection cycle, providing new insights on the genetic resistance to this disease.