Department of Animal Science


Date of this Version

January 2006


Published in 2006 Nebraska Beef Cattle Report. Copyright © 2005 The Board of Regents of the University of Nebraska.


A clinical trial was conducted within 19 Nebraska feedlots to evaluate effects of an E. coli vaccine on the probability to detect E. coli O157:H7 on ROPES or for cattle to be colonized by E. coli O157:H7 at the terminal rectum. Vaccinated pens of cattle were less likely to test ROPE-positive than nonvaccinated pens of cattle and a lower probability for E. coli O157:H7 colonization among vaccinated cattle compared with nonvaccinated cattle was observed. The vaccine was effective at reducing E. coli O157:H7 in the feedlot pen environment and colonization at the terminal rectum of cattle.