"Effect of Conjugated Linoleic Acid on Insulin Sensitivity" by Kim Hargrave and Jess L. Miner

Animal Science, Department of

 

Date of this Version

January 2002

Comments

Published in 2002 Nebraska Beef Cattle Report. Copyright © 2001 The Board of Regents of the University of Nebraska.

Abstract

Mice were fed a mixture of conjugated linoleic acid isomers (CLA) for nine weeks and then underwent an insulin tolerance test. CLA was then removed from the diet and a second insulin tolerance test was conducted following five weeks of recovery. CLA consumption impaired glucose response to insulin. When CLA was removed from the diet, insulin sensitivity of a low heat-loss genetic mouse line returned to normal. However, mice of a high heat-loss line remained insulin resistant for at least 32 days.

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