Effects of Luteinizing Hormone Releasing Hormone Antagonist On The Bovine Corpus Luteum

Authors

Debra T. Clopton, University of Nebraska-LincolnFollow
Jorge Quintal, University of Nebraska-Lincoln
Freddie Kojima, University of Nebraska-Lincoln
Karol Fike, University of Nebraska-LincolnFollow
Jim Kinder, University of Nebraska-LincolnFollow

Date of this Version

1-1-1998

Comments

Published in Nebraska Beef Cattle Report 1998, published by Agricultural Research Division, University of Nebraska Cooperative Extension, and Institute of Agriculture and Natural Resources, University of Nebraska–Lincoln.

Abstract

The size and function of the corpus luteum were examined after administration of luteinizing hormone releasing hormone antagonist. Luteinizing hormone releasing hormone antagonist was administered to three animal groups starting: 1) 2 days before the preovulatory luteinizing hormone surge inducing ovulation; 2) at initiation of the preovulatory surge; and 3) 2 days after the preovulatory surge. Although size and function of the corpus luteum were suppressed in all treated groups, the greatest developmental suppression occurred when luteinizing hormone release was blocked 2 days before the preovulatory surge of LH inducing ovulation. Therefore, optimal pregnancy rates in cattle may depend on pulsatile release of LH during the follicular phase of the estrous cycle in addition to that secreted during and after ovulation.