Biochemistry, Department of
TGD1, -2, and -3 Proteins Involved in Lipid Trafficking Form ATP-binding Cassette (ABC) Transporter with Multiple Substrate-binding Proteins
Date of this Version
The Journal of Biological Chemistry VOL. 287, NO. 25, pp. 21406–21415, June 15, 2012
Background: ATP-binding cassette transporters exist in all life forms and usually require only one substrate-binding domain.
Results: The TRIGALACTOSYLDIACYLGLYCEROL (TGD) complex contains 8–12 substrate-binding proteins.
Conclusion: Multiple substrate-binding proteins may be needed by the TGD complex to enhance its putative lipid transport activity.
Significance: Knowing the subunit stoichiometry of the TGD complex furthers understanding of lipid transfer between chloroplast membranes.
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