Biochemistry, Department of
ORCID IDs
0000-0003-2397-3131 (JEM)
Document Type
Article
Date of this Version
3-9-2012
Citation
Journal of Biological Chemistry (March 9, 2012) 287(11): 8,286–8,296
doi: 10.1074/jbcM111.274274
Abstract
Background: Sphingosine kinase (SPHK) and phospholipaseD(PLD) produce different lipid mediators involved in abscisic acid (ABA) response.
Results: Ablation of SPHKs and PLDα1 attenuates ABA-induced production of LCBPs and PA. Phyto-S1P closes stomata in sphk1, sphk2, but not in pldα1, whereas PA closes stomata in all mutants.
Conclusion: SPHK acts upstream of PLDα1, whereas PLDα1 promotes SPHK.
Significance: The roles of lipid messengers in the ABA signaling pathway are clarified.
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Comments
Copyright 2012, American Society for Biochemistry and Molecular Biology. Used by permission.