Biochemistry, Department of
Date of this Version
2012
Citation
THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 287, NO. 11, pp. 8286–8296, March 9, 2012
Abstract
Background: Sphingosine kinase (SPHK) and phospholipaseD(PLD) produce different lipid mediators involved in abscisic acid (ABA) response.
Results: Ablation of SPHKs and PLDα1 attenuates ABA-induced production of LCBPs and PA. Phyto-S1P closes stomata in sphk1, sphk2, but not in pldα1, whereas PA closes stomata in all mutants.
Conclusion: SPHK acts upstream of PLDα1, whereas PLDα1 promotes SPHK.
Significance: The roles of lipid messengers in the ABA signaling pathway are clarified.
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Comments
© 2012 by The American Society for Biochemistry and Molecular Biology, Inc.