Chemical and Biomolecular Engineering, Department of
Department of Chemical and Biomolecular Engineering: Faculty Publications
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Date of this Version
2008
Document Type
Article
Citation
Patent No.: US 7.435,869 B2
Abstract
A transgenic, non-human mammalian animal is capable of expressing a heterologous gene for human or other recombinant physiologically functional fibrinogen holoprotein or individual subunit chain polypeptides thereofora modified or fusion fibrinogen in mammary glands of the animals and secreting the expressed product into a body fluid. Methodol ogy employing such a mammal yields recombinant physiologically functional fibrinogens, subunit chain polypeptides thereof, and modified or fusion fibrinogens.
COinS
Comments
Appl. No.: 11/040,117