Surprising impact of remote groups on the folding–unfolding and dimer-chain equilibria of bifunctional H-bonding unimers

Authors

Rui Liu, State University of New York
Shuang Cheng, Nanjing University
Erin S. Baker, Pacific Northwest National Laboratory
Richard D. Smith, Pacific Northwest National Laboratory
Xiao Cheng Zeng, University of Nebraska-LincolnFollow
Bing Gong, State University of New York at BuffaloFollow

Date of this Version

2016

Citation

Chem. Commun., 2016, 52, 3773--3776

Comments

Used by permission.

Abstract

Oligoamide 1, consisting of two H-bonding units linked by a trimethylene linker, was previously found to form a very stable, folded dimer. In this work, replacing the side chains and end groups of 1 led to derivatives that show the surprising impact of end groups on the folding and dimer-chain equilibria of the resultant molecules.