Surprising impact of remote groups on the folding–unfolding and dimer-chain equilibria of bifunctional H-bonding unimers

Authors

• Rui Liu, State University of New York at Buffalo
• Shuang Cheng, Nanjing University
• Erin S. Baker, Pacific Northwest National Laboratory
• Richard D. Smith, Pacific Northwest National Laboratory
• Xiao Cheng Zeng, University of Nebraska-LincolnFollow
• Rui Liu, State University of New York at Buffalo

Document Type

Article

Date of this Version

2016

Citation

Chem Commun (Camb). 2016 March 07; 52(19): 3773–3776.

Comments

© The Royal Society of Chemistry 2016

Abstract

Oligoamide 1, consisting of two H-bonding units linked by a trimethylene linker, was previously found to form a very stable, folded dimer. In this work, replacing the side chains and end groups of 1 led to derivatives that show the surprising impact of end groups on the folding and dimer-chain equilibria of the resultant molecules.