Food Science and Technology, Department of
Department of Food Science and Technology: Faculty Publications
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Document Type
Article
Date of this Version
2018
Citation
Current Opinion in Biotechnology 2018, 49:207–216, https://doi.org/10.1016/j.copbio.2017.09.007.
Abstract
Strain-specificity of probiotic effects has been a cornerstone principle of probiotic science for decades. Certainly, some important mechanisms are present in only a few probiotic strains. But scientific advances now reveal commonalities among members of certain taxonomic groups of probiotic microbes. Some clinical benefits likely derive from these shared mechanisms, suggesting that sub-species-specific, species specific or genus-specific probiotic effects exist. Human trials are necessary to confirm specific health benefits. However, a strain that has not been tested in human efficacy trials may meet the minimum definition of the term ‘probiotic’ if it is a member of a well-studied probiotic species expressing underlying core mechanisms and it is delivered at an effective dose.
Comments
Copyright 2017 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.