Increased Dietary Trp, Thr, and Met Supplementation Improves Performance, Health, and Protein Metabolism of Weaned Piglets under Mixed Management and Poor Housing Conditions

Authors

Joseane Penteado Rosa Gonçalves, São Paulo State University
Antonio Diego Brandão Melo, São Paulo State University, University of Nebraska-Lincoln
Qinnan Yang, University of Nebraska-Lincoln
Marllon José Karpeggiane de Oliveira, São Paulo State University
Danilo Alves Marçal, São Paulo State University
Manoela Trevisan Ortiz, São Paulo State University
Pedro Righetti Arnaut, São Paulo State University
Ismael França, São Paulo State University
Graziela Alves da Cunha Valini, São Paulo State University
Cleslei Alisson Silva, São Paulo State University
Nate Korth, University of Nebraska-Lincoln
Natasha Pavlovikj, University of Nebraska-Lincoln
Paulo Henrique Reis Furtado Campos, Universidade Federal de Viçosa
Henrique Gastmann Brand, Evonik Brazil Ltd.
John Kyaw Htoo, Evonik Operations GmbH
João Carlos Gomes-Neto, University of Nebraska-Lincoln, The Ohio State University
Andrew K. Benson, University of Nebraska-LincolnFollow
Luciano Hauschild, São Paulo State University

Document Type

Article

Date of this Version

4-9-2024

Citation

Gonçalves, J.P.R.; Melo, A.D.B.; Yang, Q.; de Oliveira, M.J.K.; Marçal, D.A.; Ortiz, M.T.; Righetti Arnaut, P.; França, I.; Alves da Cunha Valini, G.; Silva, C.A.; et al. Increased Dietary Trp, Thr, and Met Supplementation Improves Performance, Health, and Protein Metabolism ofWeaned Piglets under Mixed Management and Poor Housing Conditions. Animals 2024, 14, 1143. https://doi.org/10.3390/ ani14081143

Comments

Open access.

Abstract

A sanitary challenge was carried out to induce suboptimal herd health while investigating the effect of amino acids supplementation on piglet responses. Weaned piglets of high sanitary status (6.33 ± 0.91 kg of BW) were distributed in a 2 × 2 factorial arrangement into two similar facilities with contrasting sanitary conditions and two different diets. Our results suggest that increased Trp, Thr, and Met dietary supplementation could support the immune systems of piglets under a sanitary challenge. In this manner, AA+ supplementation improved the performance and metabolism of piglets under mixed management and poor sanitary conditions. No major temporal microbiome changes were associated with differences in performance regardless of sanitary conditions or diets. Since piglets often become mixed in multiple-site production systems and facility hygiene is also often neglected, this study suggests that increased Trp, Thr, and Met (AA+) dietary supplementation could contribute to mitigating the side effects of these harmful risk factors in modern pig farms.