U.S. Department of Agriculture: Animal and Plant Health Inspection Service

 

United States Department of Agriculture Wildlife Services: Staff Publications

ORCID IDs

http://orcid.org/0000-0002-5111-9322

http://orcid.org/0000-0001-8585-1215

http://orcid.org/0000-0003-3314-8223

http://orcid.org/0000-0001-8045-5213

http://orcid.org/0000-0003-4315-8628

Document Type

Article

Date of this Version

5-20-2019

Citation

Sokolow, S.H., N. Nova, K.M. Pepin, A.J. Peel, J.R.C. Pulliam, K. Manlove, P.C. Cross, D.J. Becker, R.K. Plowright, H. McCallum, and G.A. De Leo. 2019. Ecological interventions to prevent and manage zoonotic pathogen spillover. Philosophical Transactions of the Royal Society B 374(1782):20180342. doi: 10.1098/rstb.2018.0342

Abstract

Spillover of a pathogen from awildlife reservoir into a human or livestock host requires the pathogen to overcome a hierarchical series of barriers. Interventions aimed at one or more of these barriers may be able to prevent the occurrence of spillover. Here, we demonstrate how interventions that target the ecological context in which spillover occurs (i.e. ecological interventions) can complement conventional approaches like vaccination, treatment, disinfection and chemical control. Accelerating spillover owing to environmental change requires effective, affordable, durable and scalable solutions that fully harness the complex processes involved in cross-species pathogen spillover.

This article is part of the theme issue ‘Dynamic and integrative approaches to understanding pathogen spillover’.

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