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The current study attempts to find out the research productivity and trends in Library and Information Science (LIS)subject in India during 1944 to 2017 by using bibliometric and content analysis methods. The publication data for the study was extracted from the Scopus database which consists of 1944 publications published by Indian authors.Thebibliographic data were analyzedby different bibliometric indicators which include most preferred journals, most prolific author, author collaboration trends, most prolific institutions and highly cited papers. The study reveals many important facets of LIS research in India. Gupta, B. M. the as recognized as the most prolific author with57papers; whereina context toa totalnumber of citations received Garg, K. C. topped in term of 406 citations. DESIDOC Journal of Library and Information Technolgy was identified as the most preferred journal with highest publications followed by Scientometrics Journal. The content analysis of the publications shows three major clusters in LIS research includes “Use and User study,”“Bibliometric/Scientometrics” and “Digital Library Research.”