Learning readiness is considered as a supporting factor in academic resilience. Since the situation of school closure and learning from home due to the COVID-19 pandemics, there have been changes in learning methods that require students to readily use online learning. Unfortunately, students' readiness in online learning has not been widely discussed in terms of its effect on the student’s academic resilience. The purpose of this study was to provide information on whether there was a significant relationship between online learning readiness and students' academic resilience during the school-from-home period. Participants in this study consisted of 1.681 students from five high schools in Bandung, Indonesia. The research used questionnaires that were based on the online learning readiness scale and the academic resilience scale. The questionnaires were distributed online. The data in this study were then analyzed using correlational and regression methods. The results showed that there was a moderately significant relationship between student readiness in online learning and student academic resilience during the school-from-home period. Also, online learning readiness significantly predicted student academic resilience through the dimensions of motivation for learning and self-directed learning. This study emphasized the importance of student readiness in online learning as a new learning strategy during school from home in increasing academic resilience and success.