Statistics, Department of

 

The R Journal

Date of this Version

12-2021

Document Type

Article

Citation

The R Journal (December 2021) 13(2); Editor: Dianne Cook

Comments

Copyright 2021, The R Foundation. Open access material. License: CC BY 4.0 International

Abstract

In case–control studies, the odds ratio is commonly used to summarize the association between a binary exposure and a dichotomous outcome. However, exposure misclassification frequently appears in case–control studies due to inaccurate data reporting, which can produce bias in measures of association. In this article, we implement a Bayesian sensitivity analysis of misclassification to provide a full posterior inference on the corrected odds ratio under both non-differential and differential misclassification. We present an R (R Core Team, 2018) package BayesSenMC, which provides user-friendly functions for its implementation. The usage is illustrated by a real data analysis on the association between bipolar disorder and rheumatoid arthritis.

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