National Collegiate Honors Council

 

A Mathematical Model for Antibiotic Effectiveness in Bacteria Colonies

Piseth Koy

Copyright 2021, the author

Abstract

Research titled A Mathematical Model for Antibiotic Effectiveness in Bacteria Colonies by Piseth Koy in UReCA: The NCHC Undergraduate Journal of Research and Creative Activity, 2021, pages 1-15.

STUDY SUMMARY

Description

The growth of bacteria population in a human host treated with an antibiotic depends on both: (a) the strength or the initial concentration of the antibiotic used for the treatment and (b) the profile in time of the antibiotic concentration.

Therefore both, antibiotic initial concentration, and the long-term effectiveness of the antibiotic, as its concentration decays overtime, will impact the profile of the bacteria population in the human host.

In this study we are developing a model to show the relationship between the concentration of the antibiotic Ciprofloxacin, its long-term effectiveness, and the E. coli bacteria population in a human host.

Name of antibiotic: Ciprofloxacin

Name of Bacterium: Escherichia coli