Escherichia coli O157:H7 Causes More-Severe Systemic Disease in Suckling Piglets than in Colostrum-Deprived Neonatal Piglets

Authors

Evelyn A. Dean-Nystrom, Pre-Harvest Food Safety and Enteric Diseases Research UnitFollow
Joachim F. L. Pohlenz, University of Hannover
Harley W. Moon, Iowa State UniversityFollow
Alison D. O’brien, F. Edward Hebert School of Medicine

Date of this Version

4-2000

Citation

Infection And Immunity, 68(4): Apr. 2000, P. 2356–2358

Abstract

Our objective was to determine if suckling neonatal piglets are susceptible to enterohemorrhagic Escherichia coli (EHEC) O157:H7 disease. Surprisingly, EHEC O157:H7 caused more-rapid and more-severe neurological disease in suckling neonates than in those fed an artificial diet. Shiga toxin-negative O157:H7 did not cause neurological disease but colonized and caused attaching-and-effacing intestinal lesions.