Colonization of Gnotobiotic Piglets by a luxS Mutant Strain of Escherichia coli O157:H7

Authors

Dianna M. Jordan, Iowa State University
Vanessa Sperandio, University of Maryland School of Medicine
James B. Kaper, University of Maryland School of Medicine
Evelyn A. Dean-Nystrom, Pre-Harvest Food Safety and Enteric Diseases Research UnitFollow
Harley W. Moon, Iowa State UniversityFollow

Document Type

Article

Date of this Version

2-2005

Citation

INFECTION AND IMMUNITY, 73(2): Feb. 2005, p. 1214–1216

Abstract

Gnotobiotic piglets inoculated with Escherichia coli O157:H7, its luxS mutant derivative, or nonpathogenic E. coli were evaluated for attaching and effacing lesions. Although no differences in clinical symptoms were seen between pigs inoculated with the parent and those inoculated with the luxS mutant, the luxS mutant-inoculated pigs had a lower frequency of attaching and effacing lesions in the spiral colon than parent strain-inoculated pigs.