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2007

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High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias, Hong Li, Paul N. Black, Aalap Chokshi, Angel Sandoval-Alvarez, Ravi Vatsyayan, Whitney Sealls, and Concetta DiRusso

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Mechanistic Studies of the Long Chain Acyl-CoA Synthetase Faa1p from Saccharomyces cerevisiae, Hong Li, Elaina M. Melton, Steven Quackenbush, Concetta C. DiRusso, and Paul N. Black

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Evolutionary Dynamics of Eukaryotic Selenoproteomes: Large Selenoproteomes May Associate With Aquatic Life and Small with Terrestrial Life, Alexei Lobanov, Dmitri E. Fomenko, Yan Zhang, and Aniruddha Sengupta

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Evolutionary dynamics of eukaryotic selenoproteomes: large selenoproteomes may associate with aquatic life and small with terrestrial life, Alexey V. Lobanov, Dmitri E. Fomenko, Yan Zhang, Aniruddha Sengupta, Dolph L. Hatfield, and Vadim N. Gladyshev

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Selenoprotein H Is a Nucleolar Thioredoxin-like Protein with a Unique Expression Pattern, Sergey V. Novoselov, Gregory V. Kryukov, Xue-Ming Xu, Bradley A. Carlson, Dolph L. Hatfield, and Vadim N. Gladyshev

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A highly efficient form of the selenocysteine insertion sequence element in protozoan parasites and its use in mammalian cells, Sergey V. Novoselov, Alexey V. Lobanov, Deame Hua, Marina V. Kasaikina, Dolph L. Hatfield, and Vadim Gladyshev

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Supporting Information for: A highly efficient form of the selenocysteine insertion sequence element in protozoan parasites and its use in mammalian cells, Sergey V. Novoselov, Alexey V. Lobanov, Deame Hua, Marina V. Kasaikina, Dolph L. Hatfield, and Vadim Gladyshev

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Coa1 links the Mss51 post-translational function to Cox1 cofactor insertion in cytochrome c oxidase assembly, Fabien Pierrel, Megan L. Bestwick, Paul A. Cobine, Oleh Khalimonchuk, Julia A. Cricco, and Dennis R. Winge

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NMR assignments of 1H, 13C and 15N spectra of methionine sulfoxide reductase B1 from Mus musculus, Lena S. Sal, Finn L. Aachmann, Hwa-Young Kim, Vadim N. Gladyshev, and Alexander Dikiy

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Identification and characterization of a selenoprotein family containing a diselenide bond in a redox motif, Valentina A. Shchedrina, Sergey V. Novoselov, Mikalai I. Malinouski, and Vadim N. Gladyshev

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Distinct Mechanisms for Ctr1-mediated Copper and Cisplatin Transport, Devis Sinani, David J. Adle, Heejeong Kim, and Jaekwon Lee

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Identification of Functional Subclasses in the DJ-1 Superfamily Proteins, Ying Wei, Dagmar Ringe, Mark A. Wilson, and Mary Jo Ondrechen

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Selenophosphate synthetase 2 is essential for selenoprotein biosynthesis, Xue-Ming Xu, Bradley A. Carlson, Robert Irons, Heiko Mix, Nianxin Zhong, Vadim Gladyshev, and Dolph L. Hatfield

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Biosynthesis of Selenocysteine on Its tRNA in Eukaryotes, Xue-Ming Xu, Bradley A. Carlson, Heiko Mix, Yan Zhang, Kazima Saira, Richard S. Glass, Marla J. Berry, Vadim Gladyshev, and Dolph L. Hatfield

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New Developments in Selenium Biochemistry: Selenocysteine Biosynthesis in Eukaryotes and Archaea, Xue-Ming Xu, Bradley A. Carlson, Yan Zhang, Heiko Mix, Gregory V. Kryukov, Richard S. Glass, Marla J. Berry, Vadim N. Gladyshev, and Dolph L. Hatfield

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A new strategy for assessing selenoprotein function: siRNA knockdown/knock-in targeting the 3'-UTR, MIN-HYUK YOO, XUE-MING XU, ANTON A. TURANOV, BRADLEY A. CARLSON, VADIM N. GLADYSHEV, and DOLPH L. HATFIELD

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High content of proteins containing 21st and 22nd amino acids, selenocysteine and pyrrolysine, in a symbiotic deltaproteobacterium of gutless worm Olavius algarvensis, Yan Zhang and Vadim N. Gladyshev

2006

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Purification and Initial Biochemical Characterization of ATP:Cob(I)alamin Adenosyltransferase (EutT) Enzyme of Salmonella enterica, Nicole R. Baun and Jorge C. Escalante-Semerena

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Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance, Laurence V. Bindschedler, Julia Dewdney, Kris A. Blee, Julie M. Stone, Tsuneaki Asai, Julia Plotnikov, Carine Denoux, Tezni Hayes, Chris Gerrish, Dewi R. Davies, Frederick M. Ausubel, and G. Paul Bolwell

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Studies of the CobA-Type ATP:Co(I)rrinoid Adenosyltransferase Enzyme of Methanosarcina mazei Strain Gõ1, Nicole R. Buan, Kimberly Rehfeld, and Jorge C. Escalante-Semerena

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Mammalian and other eukaryotic selenocysteine tRNAs, Bradley A. Carlson, Xue-Ming Xu, Rajeev Shrimali, Aniruddha Sengupta, Min-Hyuk Yoo, Robert Irons, Nianxin Zhong, Dolph L. Hatfield, Byeong Jae Lee, Alexei V. Lobanov, and Vadim N. Gladyshev

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Mouse models for assessing the role of selenoproteins in health and development, Bradley A. Carlson, Xue-Ming Xu, Rajeev Shrimali, Aniruddha Sengupta, Min-Hyuk Yoo, Nianxin Zhong, Dolph L. Hatfield, Robert Irons, Cindy D. Davis, Byeong Jae Lee, Sergey V. Novoselov, and Vadim N. Gladyshev

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Lysine residues in N-terminal and C-terminal regions of human histone H2A are targets for biotinylation by biotinidase, Yap Ching Chew, Gabriela Camporeale, Nagarama Kothapalli, Gautam Sarath, and Janos Zempleni

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NMR Structures of the Selenoproteins Sep15 and SelM Reveal Redox Activity of a New Thioredoxin-like Family, Andrew D. Ferguson, Vyacheslav Labunskyy, Dmitri E. Fomenko, Demet Arac, Yogarany Chelliah, Carlos A. Amexcua, Josep Rizo, Vadim N. Gladyshev, and Johann Deisenhofer

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Selenoproteins and selenoproteomes, Vadim N. Gladyshev

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"Preface" to Selenium: Its Molecular Biology and Role in Human Health, Second Edition, Dolph L. Hatfield, Marla J. Berry, and Vadim N. Gladyshev

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A Characterization of Subterranean Termites in Nebraska Using Micro-Morphological and Molecular Techniques, Timothy J. Husen, Shripat T. Kamble, and Julie M. Stone

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Microsatellite Genotyping to Distinguish Colonies and IntraSpecies Genetic Variation in the Eastern Subterranean Termite, Reticulitermes flavipes (Isoptera: Rhinotermitidae), Timothy J. Husen, Shripat T. Kamble, and Julie M. Stone

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Sequential Processing of a Mitochondrial Tandem Protein: Insights into Protein Import in Schizosaccharomyces pombe, Oleh Khalimonchuk, Martin Ott, Soledad Funes, Kai Ostermann, Gerhard Rödel, and Johannes M. Herrmann

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Alternative first exon splicing regulates subcellular distribution of methionine sulfoxide reductases, Hwa-Young Kim and Vadim Gladyshev

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Selenium and methionine sulfoxide reduction, Hwa-Young Kim and Vadim N. Gladyshev

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Hyaluronidase Expression Induces Prostate Tumor Metastasis in an Orthotopic Mouse Model, Joy L. Kovar, Mark A. Johnson, William M. Volcheck, Jiyan Chen, and Melanie A. Simpson

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The 15-kDa selenoprotein (Sep15): functional analysis and role in cancer, Vyacheslav M. Labunskyy, Vadim N. Gladyshev, and Dolph L. Hatfield

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The Plasmodium selenoproteome, Alexey V. Lobanov, Cesar Delgado, Stefan Rahlfs, Sergey V. Novoselov, Gregory V. Kryukov, Stephan Gromer, Dolph L. Hatfield, Katja Becker, and Vadim Gladyshev

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Selenium metabolism in Trypanosoma: characterization of selenoproteomes and identification of a Kinetoplastida-specific selenoprotein, Alexey V. Lobanov, Stephan Gromer, Gustavo Salinas, and Vadim Gladyshev

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Is there a twenty third amino acid in the genetic code?, Alexey V. Lobanov, Gregory V. Kryukov, Dolph L. Hatfield, and Vadim Gladyshev

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SECIS elements in the coding regions of selenoprotein transcripts are functional in higher eukaryotes, Heiko Mix, Alexey V. Lobanov, and Vadim Gladyshev

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Supplementary Material for: SECIS elements in the coding regions of selenoprotein transcripts are functional in higher eukaryotes, Heiko Mix, Alexey V. Lobanov, and Vadim Gladyshev

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Identification and characterization of Fep15, a new selenocysteine-containing member of the Sep15 protein family, Sergey V. Novoselov, Deame Hua, A. V. Lobanov, and Vadim N. Gladyshev

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S-adenosylmethionine stabilizes cystathionine β-synthase and modulates redox capacity, Anna Prudova, Zachary Bauman, Aaron Braun, Victor Vitvitsky, Shelly C. Lu, and Ruma Banerjee

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Selenoproteins in parasites, Gustavo Salinas, Alexei V. Lobanov, and Vadim N. Gladyshev

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Evolution of selenocysteine decoding and the key role of selenophosphate synthetase in the pathway of selenium utilization, Gustavo Salinas, Héctor Romero, Xue-Ming Xu, Bradley A. Carlson, Dolph L. Hatfield, and Vadim N. Gladyshev

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Concurrent Expression of Hyaluronan Biosynthetic and Processing Enzymes Promotes Growth and Vascularization of Prostate Tumors in Mice, Melanie A. Simpson

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Characterization of Alternative Cytosolic Forms and Cellular Targets of Mouse Mitochondrial Thioredoxin Reductase, Anton A. Turanov, Dan Su, and Vadim N. Gladyshev

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Methods and Materials for Making and Using Transgenic Dicamba-Degrading Organisms, Donald P. Weeks, Xiao-Zhuo Wang, and Patricia L. Herman

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Thioredoxin Reductase 1 Deficiency Reverses Tumor Phenotype and Tumorigenicity of Lung Carcinoma Cells, Min-Hyuk Yoo, Xue-Ming Xu, Bradley A. Carlson, Vadim N. Gladyshev, and Dolph L. Hatfield

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An ascorbate-reducible cytochrome b561 is localized in macrophage lysosomes, De-liang Zhang, Dan Su, Alajos Berczi , Amy Vargas , and Han H. Asard

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Dynamic evolution of selenocysteine utilization in bacteria: a balance between selenoprotein loss and evolution of selenocysteine from redox active cysteine residues, Yan Zhang, Hector Romero, Gustavo Salinas, and Vadim Gladyshev

2005

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Computer-assisted Docking of Flavodoxin with the ATP:Co(I)rrinoid Adenosyltransferase (CobA) Enzyme Reveals Residues Critical for Protein-Protein Interactions but Not for Catalysis, Nicole R. Baun and Jorge C. Escalante-Semerena

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Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism, Ekaterina I. Biterova, Anton A. Turanov, Vadim N. Gladyshev, and Joseph J. Barycki

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Computer-assisted Docking of Flavodoxin with the ATP:Co(I)rrinoid Adenosyltransferase (CobA) Enzyme Reveals Residues Critical for Protein-Protein Interactions but Not for Catalysis*, Nicole R. Buan and Jorge C. Escalante-Semerena

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Selective Rescue of Selenoprotein Expression in Mice Lacking a Highly Specialized Methyl Group in Selenocysteine tRNA, Bradley A. Carlson, Xue-Ming Xu, Vadim N. Gladyshev, and Dolph L. Hatfield

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Um34 in selenocysteine tRNA is required for the expression of stress-related selenoproteins in mammals, Bradley A. Carlson, Xue-Ming Xu, Vadim N. Gladyshev, and Dolph L. Hatfield

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Diversity and functional plasticity of eukaryotic selenoproteins: Identification and characterization of the SelJ family, Sergi Castellano, Alexey V. Lobanov, Charles Chapple, Sergey V. Novoselov, Mario Albrecht, Deame Hua, Alain Lescure, Thomas Lengauer, Alain Krol, Vadim N. Gladyshev, and Roderic Guigó

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Glycoprotein gp130 of Dictyostelium discoideum Influences Macropinocytosis and Adhesion, Catherine P. Chia, Sujatha Gomathinayagam, Robert J. Schmaltz, and Laura K. Smoyer

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Regulation of Enteric Endophytic Bacterial Colonization by Plant Defenses, A. Leonardo Iniguez, Yuemei Dong, Heather D. Carter, Brian M. M. Ahmer, Julie M. Stone, and Eric W. Triplett

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Different Catalytic Mechanisms in Mammalian Selenocysteine- and Cysteine-Containing Methionine-R-Sulfoxide Reductases, Hwa-Young Kim and Vadim Gladyshev

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pH-Dependent Substrate Preference of Pig Heart Lipoamide Dehydrogenase Varies with Oligomeric State: Response to Mitochondrial Matrix Acidification, Natalia L. Klyachko, Valentina A. Shchedrina, Alexander V. Efimov, Sergey V. Kazakov, Irina G. Gazaryan, Bruce S. Kristal, and Abraham M. Brown

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A Novel Cysteine-rich Domain of Sep15 Mediates the Interaction with UDP-glucose:Glycoprotein Glucosyltransferase, Vyacheslav M. Labunskyy, Andrew D. Ferguson, Dmitri E. Fomenko, Yogarany Chelliah, Dolph L. Hatfield, and Vadim N. Gladyshev

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Evolution of selenium utilization traits, Hector Romero, Yan Zhang, Vadim Gladyshev, and Gustavo Salinas

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Phylogenetic engineering at an interface between large and small subunits imparts land-plant kinetic properties to algal Rubisco, Robert J. Spreitzer, Srinivasa R. Peddi, and Sriram Satagopan

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Arabidopsis AtSPL14, a plant-specific SBP-domain transcription factor, participates in plant development and sensitivity to fumonisin B1, Julie M. Stone, Xinwen Liang, Emily R. Nekl, and Justin J. Stiers

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Selenocysteine insertion directed by the 3’-UTR SECIS element in Escherichia coli, Dan Su, Yehua Li, and Vadim Gladyshev

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Mammalian Selenoprotein Thioredoxin-glutathione Reductase, Dan Su, Sergey V. Novoselov, Qi-An Sun, Mohamed E. Moustafa, You Zhou, Richard Oko, Dolph L. Hatfield, and Vadim N. Gladyshev

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Nematode selenoproteome: the use of the selenocysteine insertion system to decode one codon in an animal genome?, Kalin Taskov, Charles Chapple, Gregory V. Kryukov, Sergi Castenello, Alexei V. Lobanov, Konstantin V. Korotkov, Roderic Guigo, and Vadim Gladyshev

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Evidence for Direct Roles of Two Additional Factors, SECp43 and Soluble Liver Antigen, in the Selenoprotein Synthesis Machinery, Xue-Ming Xu, Heiko Mix, Bradley A. Carlson, Paula J. Grabowski, Vadim N. Gladyshev, Marla J. Berry, and Dolph L. Hatfield

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Pyrrolysine and Selenocysteine Use Dissimilar Decoding Strategies, Yan Zhang, Pavel V. Baranov, John F. Atkins, and Vadim N. Gladyshev

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The microbial selenoproteome of the Sargasso Sea, Yan Zhang, Dmitri E. Fomenko, and Vadim Gladyshev

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An algorithm for identification of bacterial selenocysteine insertion sequence elements and selenoprotein genes, Yan Zhang and Vadim Gladyshev

2004

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The Identity of Proteins Associated with a Small Heat Shock Protein during Heat Stress in Vivo Indicates That These Chaperones Protect a Wide Range of Cellular Functions, Eman Basha, Garrett J. Lee, Linda A. Breci, Andrew C. Hausrath, Nicole R. Baun, Kim C. Giese, and Elizabeth Vierling

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The Identity of Proteins Associated with a Small Heat Shock Protein during Heat Stress in Vivo Indicates That These Chaperones Protect a Wide Range of Cellular Functions, Eman Basha, Garrett J. Lee, Linda A. Breci, Andrew C. Hausrath, Nicole R. Buan, Kim C. Giese, and Elizabeth Vierling

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The eutT Gene of Salmonella enterica Encodes an Oxygen-Labile, Metal-Containing ATP:Corrinoid Adenosyltransferase Enzyme, Nicole R. Buan, Sang-Jin Suh, and Jorge C. Escalante-Semerena

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Specific Excision of the Selenocysteine tRNA [Ser]Sec (Trsp) Gene in Mouse Liver Demonstrates an Essential Role of Selenoproteins in Liver Function, Bradley A. Carlson, Sergey V. Novoselov, Easwari Kumaraswamy, Byeong Jae Lee, Miriam R. Anver, Vadim N. Gladyshev, and Dolph L. Hatfield

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Identification and characterization of phosphoseryl-tRNA [Ser]Sec kinase, Bradley A. Carlson, Xue-Ming Xu, Gregory V. Kryukov, Mahadev Rao, Marla J. Berry, Vadim N. Gladyshev, and Dolph L. Hatfield

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Reconsidering the evolution of eukaryotic selenoproteins: a novel nonmammalian family with scattered phylogenetic distribution, Sergi Castellano, Sergey V. Novoselov, Gregory V. Kryukov, Alain Lescure, Enrique Blanco, Alain Krol, Vadim N. Gladyshev, and Roderic Guigo

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Reconsidering the evolution of eukaryotic selenoproteins: a novel nonmammalian family with scattered phylogenetic distribution, Sergi Castellano, Sergey V. Novoselov, Gregory V. Kryukov, Alain Lescure, Enrique Blanco, Alain Krol, Vadim N. Gladyshev, and Roderic Guigo

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Interactions between Small Heat Shock Protein Subunits and Substrate in Small Heat Shock Protein-Substrate Complexes, Kenneth L. Friedrich, Kim C. Giese, Nicole R. Baun, and Elizabeth Vierling

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Interactions between Small Heat Shock Protein Subunits and Substrate in Small Heat Shock Protein-Substrate Complexes, Kenneth L. Friedrich,; Kim C. Giese; Nicole R. Buan; and Elizabeth Vierling

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Identification of Methionine-rich Clusters That Regulate Copper-stimulated Endocytosis of the Human Ctr1 Copper Transporter, Yan Guo

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5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for β-oxidation of fatty acids, Peter J. Hanley, Stefan Dröse, Ulrich Brandt, Rachel A. Lareau, Abir L. Banerjee, D. K. Srivastava, Leonard J. Banaszak, Joseph J. Barycki, Paul P. Van Veldhoven, and Jürgen Daut

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Endocytic Function, Glycosaminoglycan Specificity, and Antibody Sensitivity of the Recombinant Human 190-kDa Hyaluronan Receptor for Endocytosis (HARE), Ed Harris, Janet A. Weigel, and Paul H. Weigel

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Methionine Sulfoxide Reduction in Mammals: Characterization of Methionine-R-Sulfoxide Reductases, Hwa-Young Kim and Vadim Gladyshev

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Hyaluronan Facilitates Invasion of Colon Carcinoma Cells in Vitro via Interaction with CD44, Hyeong-Rok Kim, Marie A. Wheeler, Christopher M. Wilson, Joji Iida, David Eng, Melanie A. Simpson, James B. McCarthy, and Kelli M. Bullard

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Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging, Ahmet Koc, Audrey P. Gasch, Julian C. Rutherford, Hwa-Young Kim, and Vadim N. Gladyshev

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The prokaryotic selenoproteome, Gregory V. Kryukov and Vadim N. Gladyshev

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A Role for Talin in Presynaptic Function, Jennifer R. Morgan, Gilbert Di Paolo, Hauke Werner, Valentina A. Shchedrina, Marc Pypaert, Vincent A. Pieribone, and Pietro De Camilli

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Mobilization of Intracellular Copper Stores by the Ctr2 Vacuolar Copper Transporter, Erin M. Rees, Jaekwon Lee, and Dennis J. Thiele

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Characterization of Human UDP-glucose Dehydrogenase: CYS-276 Is Required for the Second of Two Successive Oxidations, Brandi J. Sommer, Joseph J. Barycki, and Melanie A. Simpson

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Tissue-specific expression and developmental regulation of cytochrome b561 genes in Arabidopsis thaliana and Raphanus sativus, Wim Verelst, Jyoti Kapila, Janice De Almeida Engler, Julie M. Stone, Roland Caubergs, and Han Asard

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Melanoma chondroitin sulfate proteoglycan enhances FAK and ERK activation by distinct mechanisms, Jianbo Yang, Matthew A. Price, Cheryl L. Neudauer, Christopher Wilson, Soldano Ferrone, Hong Xia, Joji Iida, Melanie A. Simpson, and James B. McCarthy

2003

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THE MANY FACES OF VITAMIN B12: CATALYSIS BY COBALAMIN-DEPENDENT ENZYMES, Ruma Banerjee and Stephen W. Ragsdale

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Transmembrane Movement of Exogenous Long-Chain Fatty Acids: Proteins, Enzymes, and Vectorial Esterification, Paul N. Black and Concetta C. DiRusso

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Characterization of Mammalian Selenoproteomes, Gregory V. Kryukov, Sergi Castellano, Sergey V. Novoselov, Alexey V. Lobanov, Omid Zehtab, Roderic Guigo, and Vadim N. Gladyshev

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Selective Removal of the Selenocysteine tRNA [Ser]Sec Gene (Trsp) in Mouse Mammary Epithelium, Easwari Kumaraswamy, Bradley A. Carlson, Fanta Morgan, Keiko Miyoshi, Gertraud W. Robinson, Dan Su, Shulin Wang, Eileen Southon, Lino Tessarollo, Byeong Jae Lee, Vadim Gladyshev, Lothar Hennighausen, and Dolph L. Hatfield

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The Drosophila Selenoprotein BthD Is Required for Survival and Has a Role in Salivary Gland Development, So Yeon Kwon, Paul Badenhorst, F. Javier Martin-Romero, Bradley A. Carlson, Bruce M. Paterson, Vadim Gladyshev, Byeong Jae Lee, and Dolph L. Hatfield

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RacB Regulates Cytoskeletal Function in Dictyostelium spp., Eunkyung Lee, David J. Seastone, Ed Harris, James A. Cardelli, and David A. Knecht

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Chlamydomonas reinhardtii selenocysteine tRNA [Ser]Sec, Mahadev Rao, Bradley A. Carlson, Sergey V. Novoselov, Donald P. Weeks, Vadim Gladyshev, and Dolph L. Hatfield

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Functional copper at the acetyl-CoA synthase active site, Javier Seravalli, Welwel Gu, Annie Tam, Erick Strauss, Stephen P. Cramer, and Stephen W. Ragsdale

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A phylogenetic study of cytochrome b561 proteins, Wim Verelst and Han H. Asard

2002

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The insulation of genes from external enhancers and silencing chromatin, Bonnie Burgess-Beusse, Catherine Farrell, Miklos Gaszner, Michael Litt, Vesco Mutskov, Felix Recillas - Targa, Melanie Simpson, Adam West, and Gary Felsenfeld