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The R Journal

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Date of this Version

6-2021

Document Type

Article

Citation

The R Journal (June 2021) 13(1); Editor: Dianne Cook

Comments

Copyright 2021, The R Foundation. Open access material. License: CC BY 4.0 International

Abstract

The goal of this paper is to help define a path toward a grammar for processing clinical trials by a) defining a format in which we would like to represent data from standardized clinical trial data b) describing a standard set of operations to transform clinical trial data into this format, and c) to identify a set of verbs and other functionality to facilitate data processing and encourage reproducibility in the processing of these data. It provides a background on standard clinical trial data and goes through a simple preprocessing example illustrating the value of the proposed approach through the use of the forceps package, which is currently being used for data of this kind.

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