Patrick H. Dussault

Professor & Department Chair
551/829 Hamilton Hall
University of Nebraska-Lincoln

patrick.dussault@unl.edu

Dussault Research Group website: http://www.chem.unl.edu/phd/

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2015

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Dietary Plant Sterol Esters Must Be Hydrolyzed to Reduce Intestinal Cholesterol Absorption in Hamsters, Trevor J. Carden, Jiliang Hang, Patrick Dussault, and Timothy P. Carr

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Fatty Acyl Incorporation in the Biosynthesis of WAP-8294A, a Group of Potent Anti-MRSA Cyclic Lipodepsipeptides, Haotong Chen, Andrew S. Olson, Wei Su, Patrick Dussault, and Liangcheng Du

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Synthesis of Ethers via Reaction of Carbanions and Monoperoxyacetals, ShivaKumar Kyasa, Rebecca N. Meier, Ruth A. Pardini, Tristan K. Truttmann, Keith T. Kuwata, and Patrick Dussault

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Synthesis of a 2,4,6,8,10-dodecapentanoic acid thioester as a substrate for biosynthesis of heat stable antifungal factor (HSAF), Andrew S. Olson, Haotong Chen, Liangcheng Du, and Patrick Dussault

2014

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β-Keto and β-hydroxyphosphonate analogs of biotin-5’-AMP are inhibitors of holocarboxylase synthetase, Wantanee Sittiwong, Elizabeth Cordonier, Janos Zempleni, and Patrick Dussault

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Oxacycle Synthesis via Intramolecular Reaction of Carbanions and Peroxides, Rachel Willand-Charnley, Benjamin W. Puffer, and Patrick Dussault

2013

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Design and Synthesis of a New Class of Twin-Chain Amphiphiles for Self-Assembled Monolayer-based Electrochemical Biosensor Applications, Thomas J. Fisher, Socrates Jose P. Cañete, Rebecca Lai, and Patrick Dussault

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Synthesis Of Alkyl Hydroperoxides Via Alkylation Of gem-Dihydroperoxides, ShivaKumar Kyasa, Benjamin W. Puffer, and Patrick Dussault

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Re2O7-catalyzed reaction of hemiacetals and aldehydes with O-, S-, and C-nucleophiles, Wantanee Sittiwong, Michael W. Richardson, Charles E. Schiaffo, Thomas J. Fisher, and Patrick Dussault

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Tandem application of C-C bond-forming reactions with reductive ozonolysis, Rachel Willand-Charnley and Patrick Dussault

2012

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Regioselective Synthesis of Tetraalkynylarenes by Consecutive Dual Sonogashira Coupling Reactions of the Bis(triflate) of 4,5-Diiodobenzene-1,2-diol, Thomas J. Fisher and Patrick H. Dussault

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Generation of singlet oxygen from fragmentation of monoactivated 1,1-dihydroperoxides, Jiliang Hang, Prasanta Ghorai, Solaire A. Finkenstaedt-Quinn, Ilhan Findik, Emily Sliz, Keith T. Kuwata, and Patrick Dussault

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In vitro and in vivo activity of 3-alkoxy-1,2- dioxolanes against Schistosoma mansoni, Katrin Ingram, Charles E. Schiaffo, Wantanee Sittiwong, Evan Benner, Patrick Dussault, and Jennifer Keiser

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Pyridine is an organocatalyst for the reductive ozonolysis of alkenes, Rachel Willand-Charnley, Thomas J. Fisher, Bradley M. Johnson, and Patrick Dussault

2011

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Phytosterol stearate esters elicit similar responses on plasma lipids and cholesterol absorption but different responses on fecal neutral sterol excretion and hepatic free cholesterol in male Syrian hamsters, Mark M. Ash, Jiliang Hang, Patrick Dussault, and Timothy P. Carr

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Reversible collapse of the Langmuir films of a series of triphenylsilyl ether-terminated amphiphiles, Christine A. DeVries, James J. Haycraft, Qiang Han, Farhana Noor-e-Ain, Joseph Raible, Patrick Dussault, and Craig J. Eckhardt

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N5-Phosphonoacetyl-L-ornithine (PALO): A convenient synthesis and investigation of influence on regulation of amino acid biosynthetic genes in Saccharomyces cerevisiae, Brad Johnson, Rachel Steadman, Krista D. Patefield, Jeffrey J. Bunker, Audrey L. Atkin, and Patrick Dussault

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A Mild One-Pot Conversion of Alkenes into Amines through Tandem Ozonolysis and Reductive Amination, ShivaKumar Kyasa, Thomas J. Fisher, and Patrick Dussault

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Biosynthesis of HSAF, a Tetramic Acid-containing Macrolactam from Lysobacter enzymogenes, Lili Lou, Guoliang Qian, Yunxuan Xie, Jiliang Hang, Haotong Chen, Kathia Zaleta- Rivera, Yaoyao Li, Yuemao Shen, Patrick Dussault, Fengquan Liu, and Liangcheng Du

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3-Alkoxy-1,2-Dioxolanes: Synthesis and Evaluation as Potential Antimalarial Agents, Charles E. Schiaffo, Matthias Rottman, Sergio Wittlin, and Patrick Dussault

2010

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Plant sterol and stanol substrate specificity of pancreatic cholesterol esterase, Andrew W. Brown, Jiliang Hang, Patrick H. Dussault, and Timothy P. Carr

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Fragmentation of chloroperoxides: Hypochlorite-mediated dehydration of hydroperoxyacetals to esters, Thomas J. Fisher and Patrick Dussault

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A concise synthesis of β-sitosterol and other phytosterols, Jiliang Hang and Patrick Dussault

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Efficient synthesis and conformational investigations of cis-pentacenediols, Jinyue Jiang, Charles E. Schiaffo, Chris P. Schwartz, Yong Pei, Joseph J. Dumais, Xiao Cheng Zeng, Patrick Dussault, and Li Tan

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B(C6F5)3-promoted tandem silylation and intramolecular hydrosilylation: diastereoselective synthesis of oxasilinanes and oxasilepanes, Roman Shchepin, Chunping Xu, and Patrick Dussault

2009

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Spiroadamantyl 1,2,4-trioxolane, 1,2,4-trioxane, and 1,2,4-trioxepane pairs: Relationship between peroxide bond iron(II) reactivity, heme alkylation efficiency, and antimalarial activity, Xiaofang Wang, Darren J. Creek, Charles E. Schiaffo, Yuxiang Dong, Jacques Chollet, Christian Scheurer, Segio Wittlin, Susan A. Charman, Patrick Dussault, James K. Wood, and Jonathan L. Vennerstrom

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Asymmetric synthesis of 1,2-dioxanes: Approaches to the peroxyplakoric acids, Chunping Xu, Chris Schwartz, Joseph Raible, and Patrick Dussault

2008

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Influence of heterocyclic and oxime-containing farnesol analogs on quorum sensing and pathogenicity in Candida albicans, Roman Shchepin, Dhammika H.M.L.P. Navarathna, Raluca Dumitru, Shane Lippold, Kenneth W. Nickerson, and Patrick Dussault

2007

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Cholesterol-lowering properties of plant sterols esterified with beef tallow fatty acids in hamsters, David M. Guderian Jr., Heather E. Rasmussen, Curtis A. Wray, Patrick Dussault, and Timothy P. Carr

2006

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“Reductive ozonolysis” via a new fragmentation of carbonyl oxides, Chris Schwartz, Joseph Raible, Kyle Mott, and Patrick Dussault

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A Bidomain Nonribosomal Peptide Synthetase Encoded by FUM14 Catalyzes the Formation of Tricarballylic Esters in the Biosynthesis of Fumonisins, Kathia Zaleta-Rivera, Chunping Xu, Fengan Yu, Robert A. E. Butchko, Robert H. Proctor, Maria E. Hidalgo-Lara, Ashraf S. Raza, Patrick Dussault, and Liangcheng Du

2005

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Stereoselective allylation of chiral monoperoxyacetals, Aqeel Ahmed and Patrick Dussault

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Biologically Active Fluorescent Farnesol Analogs, Roman Shchepin, Razvan Dumitru, Kenneth W. Nickerson, Miranda Lund, and Patrick Dussault

2004

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Magnesium/Methanol: An Effective Reducing Agent for Peroxides , Peng Dai, Patrick Dussault, and Tony K. Trullinger

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Curtius rearrangement and Wolff homologation of functionalized peroxides, Patrick Dussault and Chunping Xu

2001

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Quorum Sensing in the Dimorphic Fungus Candida albicans Is Mediated by Farnesol, Jacob M. Hornby, Ellen C. Jensen, Amber C. Lisec, Joseph J. Tasto, Brandon Jahnke, Richard Shoemaker, Patrick Dussault, and Kenneth W. Nickerson