Follow

2016

PDF

A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris, Fabrice Cerini, Hubert Gaertner, Knut Madden, Ilya Tolstorukov, Scott Brown, Bram Laukens, Nico Callewaert, Jay C. Harner, Anna M. Oommen, John T. Harms, Anthony R. Sump, Robert C. Sealock, Dustin J. Peterson, Scott K. Johnson, Stephan B. Abramson, Michael M. Meagher, Robin Offord, and Oliver Hartley

PDF

Hyaluronic acid-conjugated liposome nanoparticles for targeted delivery to CD44 overexpressing glioblastoma cells, Stephen L. Hayward, Christina L. Wilson, and Srivatsan Kidambi

PDF

Scalable Production of Glioblastoma Tumor-initiating Cells in 3 Dimension Thermoreversible Hydrogels, Qiang Li, Haishuang Lin, Ou Wang, Xuefeng Qiu, Srivatsan Kidambi, Loic P. Deleyrolle, Brent A. Reynolds, and Yuguo Lei

PDF

Decoy receptor DcR1 is induced in a p50/Bcl3-dependent manner and attenuates the efficacy of temozolomide, Nassir M. Mansour, Giovanna M. Bernal, Longtao Wu, Clayton D. Crawley, Kirk E. Cahill, David J. Voce, Irina V. Balyasnikova, Wei Zhang, Ruben Spretz, Luis Nunez, Gustavo Larsen, Ralph R. Weichselbaum, and Bakhtiar Yamini

PDF

Characterization of IXINITY (Trenonacog Alfa), a Recombinant Factor IX with Primary Sequence Corresponding to the Threonine-148 Polymorph, Dougald M. Monroe, Richard J. Jenny, Kevin Van Cott, Shelly Buhay, and Laura L. Saward

PDF

Retargeting the Clostridium botulinum C2 toxin to the neuronal cytosol, Benjamin J. Pavlik, Elizabeth J. Hruska, Kevin Van Cott, and Paul Helmuth Blum

PDF

Diurnal Regulation of Cellular Processes in the Cyanobacterium Synechocystis sp. Strain PCC 6803: Insights from Transcriptomic, Fluxomic, and Physiological Analyses, Rajib Saha, Deng Liu, Allison Hoynes-O’Connor, Michelle Liberton, Jingjie Yu, Maitrayee Bhattacharyya-Pakrasi, Andrea Balassy, Fuzhong Zhang, Tae Seok Moon, Costas D. Maranas, and Himadri B. Pakrasi

PDF

Astrogliosis in a dish: Substrate stiffness induces astrogliosis in primary rat astrocytes, Christina L. Wilson, Stephen L. Hayward, and Srivatsan Kidambi

2015

PDF

Energy intensity and environmental impact metrics of the back-end separation of ethylene plant by thermodynamic analysis, Mahdi H. Alhajji and Yaşar Demirel

PDF

Cyanobacterial Alkanes Modulate Photosynthetic Cyclic Electron Flow to Assist Growth under Cold Stress, Bertram M. Berla, Rajib Saha, Costas D. Maranas, and Himadri B. Pakrasi

PDF

Breast Cancer/Stromal Cells Coculture on Polyelectrolyte Films Emulates Tumor Stages and miRNA Profiles of Clinical Samples, Amita Daverey, Karleen M. Brown, and Srivatsan Kidambi

PDF

Physical Intimacy of Breast Cancer Cells with Mesenchymal Stem Cells Elicits Trastuzumab Resistance through Src Activation, Amita Daverey, Allison P. Drain, and Srivatsan Kidambi

PDF

Titanium Dioxide Nanoparticles Trigger Loss of Function and Perturbation of Mitochondrial Dynamics in Primary Hepatocytes, Vaishaali Natarajan, Christina L. Wilson, Stephen L. Hayward, and Srivatsan Kidambi

PDF

Growth factor and ultrasound-assisted bioreactor synergism for human mesenchymal stem cell chondrogenesis, Sanjukta Guha Thakurta, Gaurav Budhiraja, and Anuradha Subramanian

PDF

Quantifying Vitamin K-dependent Holoprotein Compaction caused by differential γ-carboxylation using HPSEC, Nicholas C. Vanderslice, Amanda S. Messer, Kanagasabai Vadivel, S. Paul Bajaj, Martin Phillips, Mostafa Fatemi, Weijie Xu, and William H. Velander

PDF

Mitochondrial dysfunction and loss of glutamate uptake in primary astrocytes exposed to titanium dioxide nanoparticles, Christina L. Wilson, Vaishaali Natarajan, Stephen L. Hayward, Oleh Khalimonchuk, and Srivatsan Kidambi

PDF

Engineering protein processing of the mammary gland to produce abundant hemophilia B therapy in milk, Jianguo Zhao, Weijie Xu, Jason W. Ross, Eric M. Walters, Stephen P. Butler, Jeff J. Whyte, Lindsey Kelso, Mostafa Fatemi, Nicholas C. Vanderslice, Keith Giroux, Lee D. Spate, Melissa S. Samuel, Cliff N. Murphy, Kevin D. Wells, Nick C. Masiello, Randall S. Prather, and William H. Velander

2014

PDF

Convection enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma, Giovanna M. Bernal, Michael J. LaRiviere, Nassir Mansour, Peter Pytel, Kirk E. Cahill, David J. Voce, Shijun Kang, Rubin Spretz, Ulrich Welp, Sandra E. Noriega, Luis Nunez, Gustavo F. Larsen, Ralph R. Weichselbaum, and Bakhtiar Yamini

PDF

Developing Defined and Scalable 3D Culture Systems for Culturing Human Pluripotent Stem Cells at High Densities, Yuguo Lei, Daeun Jeong, Jifang Xiao, and David V. Schaffer

PDF

Assessing the Metabolic Impact of Nitrogen Availability Using a Compartmentalized Maize Leaf Genome-Scale Model, Margaret Simmons, Rajib Saha, Nardjis Amiour, Akhil Kumar, Lenaïg Guillard, Gilles Clément, Martine Miquel, Zhenni Li, Gregory Mouille, Peter J. Lea, Bertrand Hirel, and Costas D. Maranas

PDF

Tactile Imaging of an Imbedded Palpable Structure for Breast Cancer Screening, Chieu Van Nguyen and Ravi Saraf

PDF

Development of a Fatal Noncompressible Truncal Hemorrhage Model with Combined Hepatic and Portal Venous Injury in Normothermic Normovolemic Swine, Ujwal R. Yanala, Jason M. Johanning, Iraklis I. Pipinos, Gustavo Larsen, William H. Velander, and Mark A. Carlson

PDF

Development of a Fatal Noncompressible Truncal Hemorrhage Model with Combined Hepatic and Portal Venous Injury in Normothermic Normovolemic Swine, Ujwal R. Yanala, Jason M. Johanning, Iraklis I. Pipinos, Gustavo Larsen, William H. Velander, and Mark A. Carlson

2013

PDF

Synthetic biology of cyanobacteria: unique challenges and opportunities, Bertram M. Berla, Rajib Saha, Cheryl M. Immethun, Costas D. Maranas, Tae Seok Moon, and Himadri B. Pakras

PDF

In vitro evaluation of PEGylated mesoporous MgFe2O4 magnetic nanoassemblies (MMNs) for chemo-thermal therapy, Sunil Kumar, Amita Daverey, Niroj Kumar Sahu, and Dhirendra Bahadur

PDF

A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation, Yuguo Lei and David V. Schaffer

PDF

Mechanotransduction of Ultrasound is Frequency Dependent Below the Cavitation Threshold, Tobias M. Louw, Gaurav Budhiraja, Hendrik J. Viljoen, and Anuradha Subramanian

PDF

New Potential Therapeutic Approach for the Treatment of B-Cell Malignancies Using Chlorambucil/ Hydroxychloroquine-Loaded Anti-CD20 Nanoparticles, Nelly Mezzaroba, Sonia Zorzet, Erika Secco, Stefania Biffi, Claudio Tripodo, Marco Calvaruso, Ramiro Mendoza-Maldonado, Sara Capolla, Marilena Granzotto, Ruben Spretz, Gustavo Larsen, Sandra Noriega, Marianna Lucafó, Eduardo Mansilla, Chiara Garrovo, Gustavo H. Marín, Gabriele Bai, Valter Gattei, Gabriele Pozzato, Luis Núñez, and Paolo Macor

PDF

The Effect of Ultrasound Stimulation on the Cytoskeletal Organization of Chondrocytes Seeded In 3D Matrices, Sandra Noriega, Gulnara Hasanova, and Anuradha Subramanian

PDF

Ultrasonic Bioreactor as a Platform for Studying Cellular Response, Anuradha Subramanian, Joseph A. Turner, Gaurav Budhiraja, Sanjukta Guha Thakurta, Nicholas P. Whitney, and Sai Siddhartha Nudurupati

2012

PDF

Forced wave motion with internal and boundary damping, Tobias Louw, Scott Whitney, Anu Subramanian, and Hendrik Viljoen

PDF

Remodeling of chromatin under low intensity diffuse ultrasound, Sandra Noriega, Gaurav Budhiraja, and Anuradha Subramanian

PDF

Effect of Fiber Diameter on the Spreading, Proliferation and Differentiation of Chondrocytes on Electrospun Chitosan Matrices, Sandra E. Noriega, Gulnara I. Hasanova, Min Jeong Schneider, Gustavo F. Larsen, and Anuradha Subramanian

PDF

Generalized ellipsometry in-situ quantification of organic adsorbate attachment within slanted columnar thin films, Keith B. Rodenhausen Jr., Daniel Schmidt, Tadas Kasputis, Angela K. Pannier, Eva Schubert, and Mathias Schubert

PDF

Reconstruction and Comparison of the Metabolic Potential of Cyanobacteria Cyanothece sp. ATCC 51142 and Synechocystis sp. PCC 6803, Rajib Saha, Alex T. Verseput, Bertram M. Berla, Thomas J. Mueller, Himadri B. Pakrasi, and Costas D. Maranas

PDF

Design and Characterization of Micro-Porous Hyaluronic Acid Hydrogels for in vitro Gene Transfer to mMSCs, Talar Tokatlian, Cynthia Cam, Shayne N. Siegman, Yuguo Lei, and Tatiana Segura

PDF

Integrin-mediated mechanotransduction pathway of low-intensity continuous ultrasound in human chondrocytes, Nicholas P. Whitney, Allyson C. Lamb, Tobias M. Louw, and Anuradha Subramanian

2011

PDF

The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels, Yuguo Lei, Shiva Gojgini, Jonathan Lam, and Tatiana Segura

PDF

Hyaluronic Acid and Fibrin Hydrogels with Concentrated DNA/ PEI Polyplexes for Local Gene Delivery, Yuguo Lei, Maha Rahim, Quinn Ng, and Tatiana Segura

PDF

Experimental Validation of a Fundamental Model for PCR Efficiency, Tobias M. Louw, Christine S. Booth, Elsje Pienaar, Joel R. TerMaat, Scott E. Whitney, and Hendrik J. Viljoen

PDF

Could Metabolic Syndrome, Lipodystrophy, and Aging Be Mesenchymal Stem Cell Exhaustion Syndromes?, Eduardo Mansilla, Vanina Díaz Aquino, Daniel Zambón, Gustavo Horacio Marin, Karina Mártire, Gustavo Roque, Thomas Ichim, Neil H. Riordan, Amit Patel, Flavio Sturla, Gustavo Larsen, Rubén Spretz, Luis Núñez, Carlos Soratti, Ricardo Ibar, Michiel van Leeuwen, José María Tau, Hugo Drago, and Alberto Maceira

PDF

Process Development and cGMP Manufacturing of a Recombinant Ricin Vaccine: an Effective and Stable Recombinant Ricin A-Chain Vaccine—RVEcTM, Michael M. Meagher, Javier G. Seravalli, S. Todd Swanson, Roger G. Ladd, Yogender P. Khasa, Mehmet Inan, Jay C. Harner, Scott K. Johnson, Kevin Van Cott, Changhong Lindsey, Robert Wannemacher, and Leonard A. Smith

PDF

Using Thermally Coupled Reactive Distillation Columns in Biodiesel Production, Nghi Nguyen and Yaşar Demirel

PDF

A Novel Biodiesel and Glycerol Carbonate Production Plant, Nghi T. Nguyen and Yasar Demirel

PDF

Impact of Porogens on the Pore Characteristics of Zirconia Particles Made by Polymer-Induced Colloid Aggregation, Abhinandan Pattanayak and Anuradha Subramanian

PDF

Functional factor VIII made with von Willebrand factor at high levels in transgenic milk, Steven W. Pipe, Hongzhi Miao, Stephen P. Butler, Jennifer Calcaterra, and William H. Velander

PDF

Combined optical and acoustical method for determination of thickness and porosity of transparent organic layers below the ultra-thin film limit, Keith B. Rodenhausen Jr., Tadas Kasputis, Angela K. Pannier, J. Y. Gerasimov, R. Y. Lai, M. Solinsky, T. E. Tiwald, H. Wang, Amitabha Sarkar, Tino Hofmann, Natale J. Ianno, Mathias Schubert, and Jennifer Y. Gerasimov

PDF

Zea mays iRS1563: A Comprehensive Genome-Scale Metabolic Reconstruction of Maize Metabolism, Rajib Saha, Patrick F. Suthers, and Costas D. Maranas

PDF

Improved cellular infiltration into nanofibrous electrospun crosslinked gelatin scaffolds templated with micrometer sized polyethylene glycol fibers, Maciej Skotak, Jorge Ragusa, Daniela Gonzalez, and Anuradha Subramanian

2010

PDF

Efficiency of the Polymerase Chain Reaction, Christine S. Booth, Elsje Pienaar, Joel R. Termaat, Scott E. Whitney, Tobias M. Louw, and Hendrik J. Vijoen

PDF

Nonequilibrium Thermodynamics Modeling of Coupled Biochemical Cycles in Living Cells, Yaşar Demirel

PDF

High throughput quantification of N-glycans using one-pot sialic acid modification and matrix assisted laser desorption ionization time of flight mass spectrometry, Geun-Cheol Gil, Bryce Iliff, Ron Cerny, William H. Velander, and Kevin Van Cott

PDF

Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate, Pieter P. Jacobs, Mehmet Inan, Nele Festjens, Jurgen Haustraete, Annelies Van Hecke, Roland Contreras, Michael M. Meagher, and Nico Callewaert

PDF

Propofol induces MAPK/ERK cascade dependant expression of cFos and Egr-1 in rat hippocampal slices, Srivatsan Kidambi, Joel Yarmush, Yevgeny Berdichevsky, Sangeetha Kamath, Wayne Fong, and Joseph SchianodiCola

PDF

Incorporation of Active DNA/Cationic Polymer Polyplexes into Hydrogel Scaffolds, Yuguo Lei, Suxian Huang, Pooria Sharif-Kashani, Yong Chen, Pirouz Kavehpour, and Tatiana Segura

PDF

Two and Three-dimensional Gene Transfer from Enzymatically Degradable Hydrogel Scaffolds, Yuguo Lei, Quinn K.T. Ng, and Tatiana Segura

PDF

Retrofit of Distillation Columns in Biodiesel Production Plants, Nghi Nguyen and Yaşar Demirel

PDF

A Model of Tuberculosis Transmission and Intervention Strategies in an Urban Residential Area, Elsje Pienaar, Aaron M. Fluitt, Scott E. Whitney, Alison G. Freifeld, and Hendrik J. Viljoen

2009

PDF

Thermodynamically coupled heat and mass flows in a reaction-transport system with external resistances, Yasar Demirel

PDF

N-glycosylation microheterogeneity and site occupancy of an Asn-X-Cys sequon in plasma-derived and recombinant protein C, Geun-Cheol Gil, William H. Velander, and Kevin E. Van Cott

PDF

Propofol induces ERK-dependant expression of c-Fos and Egr-1 in neuronal cells, Srivatsan Kidambi, Joel Yarmush, Wayne Fong, Sangeetha Kamath, Joseph SchianodiCola, and Yaakov Nahmias

PDF

Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance, Srivatsan Kidambi, Rubin S. Yarmush, Eric Novik, Piyun CHao, Martin L. Yarmush, and Yaakov Nahmias

PDF

DNA Delivery from Matrix Metalloproteinase Degradable Poly (ethylene glycol) Hydrogels to Mouse Cloned Mesenchymal Stem Cells, Yuguo Lei and Tatiana Segura

PDF

Gene synthesis by integrated polymerase chain assembly and PCR amplification using a high-speed thermocycler, Joel R. TerMaat, Elsje Pienaar, Scott E. Whitney, Tarlan G. Mamedov, and Anuradha Subramanian

PDF

A kinetic study of in vitro lysis of Mycobacterium smegmatis , William J. Valente, Elsje Pienaar, A. Fast, A. Fluitt, Scott E. Whitney, Robert J. Fenton, Raul G. Barletta, O. Chacon, and Hendrik J. Viljoen

2008

PDF

Modeling of thermodynamically coupled reaction-transport systems, Yasar Demirel

PDF

Thermodynamically Coupled Transport in Simple Catalytic Reactions, Yasar Demirel

PDF

Analysis of the N-glycans of recombinant human Factor IX purified from transgenic pig milk, Geun-Cheol Gil, William H. Velander, and Kevin Van Cott

PDF

Tunable Resistive m-dPEG Acid Patterns on Polyelectrolyte Multilayers at Physiological Conditions: Template for Directed Deposition of Biomacromolecules, Srivatsan Kidambi, Christina Chan, and Ilsoon Lee

PDF

Primary Neuron/Astrocyte Co-Culture on Polyelectrolyte Multilayer Films: A Template for Studying Astrocyte-Mediated Oxidative Stress in Neurons, Srivatsan Kidambi, Ilsoon Lee, and Christina Chan

PDF

Polyelectrolyte mediated scalable synthesis of highly stable silver nanocubes in less than a minute using microwave irradiation, Subrata Kundu, Vivek C. Maheshwari, Sanjun Niu, and Ravi Saraf

PDF

Web-based applications for building, managing and analysing kinetic models of biological systems, Dong-Yup Lee, Rajib Saha, Faraaz Noor Khan Yusufi, Wonjun Park, and IftekharA. Karimi

PDF

Cell Adhesion On Surfaces Of Varying Topographies, Ilsoon Lee, Christina Chan, and Srivatsan Kidambi

PDF

Self-Assembly of a Micrometers-Long One-Dimensional Network of Cemented Au Nanoparticles, Vivek Maheshwari, Jennifer Kane, and Ravi Saraf

PDF

A Fundamental Study of the PCR Amplification of GC-rich DNA Templates, T. G. Mamedov, Elsje Pienaar, Scott E. Whitney, Joel R. TerMaat, G. Carvill, R. Goliath, A. Subramanian, and Hendrik J. Viljoen

PDF

Control On Platelet Adhesion And Activation Events By Selective And Specific Binding Of Plasma Protein On Peptide-Coupled Surface, Anuradha Subramanian and Sanjukta Guha-Thankruta

PDF

Importance of Annealing Times in the PCR Amplification of GC-Rich Genes, Anuradha Subramanian, Tarlan Mamedov, Elsje Pinnear, and Hendrik Viljoen

PDF

Characterization of a Polymer Surface With Sequentially Immobilized Proteins, Anuradha Subramanian, Tarlan Mammedov, and Karl E. Kador

PDF

Effect Of Intermittent Applications Of Continuous Ultrasound Signal On The Morphology And Cytoskeletal Organization In Chondrocytes, Anuradha Subramanian, Sandra Noriega, and Gulnara Hasanova

2007

PDF

Salt And pH Tunable Resist Patterns On Polyelectrolyte Multilayers, Christina Chan, Ilsoon Lee, and Srivatsan Kidambi

PDF

Thermoeconomics of seasonal latent heat storage system, Dr.Yasar Demirel and H. Huseyin Ozturk

PDF

Identification and characterization of calcium and manganese transporting ATPase (PMR1) gene of Pichia pastoris, Michael P. Dux and Mehmet Inan

PDF

Ribosome kinetics and aa-tRNA competition determine rate and fidelity of peptide synthesis, Aaron Fluitt, Elsje Pienaar, and Hendrik J. Viljoen

PDF

Detection of ultrathin biological films using vacuum ultraviolet spectroscopic ellipsometry, Dileep K. Goyal, Greg K. Pribil, John A. Woollam, and Anuradha Subramanian

PDF

Effect of Hydrofluoric Acid in Oxidizing Acid Mixtures on the Hydroxylation of Silicon Surface, Sanjukta Guhathakurta and Anuradha Subramanian

PDF

Cell Adhesion on Polyelectrolyte Multilayer Coated Polydimethylsiloxane Surfaces with Varying Topographies, Srivatsan Kidambi, Natasha Udpa, Stacey A. Schroeder, Robert Findlan, Ilsoon Lee, and Christina Chan

PDF

Rational de novo gene synthesis by rapid polymerase chain assembly (PCA) and expression of endothelial protein-C and thrombin receptor genes, Tarlan G. Mamedov, Nisha V. Padhye, Hendrik Viljoen, and Anuradha Subramanian

PDF

Selective assembly of nanoparticles on block copolymer by surface modification, Sanjun Niu and Ravi Saraf

PDF

Developement of serum-free media in CHO-DG44 cells using a central composite statistical design, Ananth Parampalli, Kent M. Eskridge, Leonard Smith, Michael M. Meagher, M. C. Mowry, and Anuradha Subramanian

PDF

The tri-frame model, Elsje Pienaar and Hendrik J. Viljoen

PDF

Linear Tactile Nanodevice with Resolution on Par with Human Finger, Ravi Saraf, Vivek C. Maheshwari, and Chieu Nguyen

PDF

Cell bank characterization and fermentation optimization for production of recombinant heavy chain C-terminal fragment of botulinum neurotoxin serotype E (rBoNTE(Hc): Antigen E) by Pichia pastoris, Jayanta Sinha, Mehmet Inan, Sarah Fanders, Shinichi Taoka, Mark Gouthro, Todd Swanson, Rick Barent, Ardis Barthuli, Bonnie M. Loveless, Leonard A. Smith, Theresa Smith, Ian Henderson, John Ross, and Michael M. Meagher

PDF

Protection with Recombinant Clostridium botulinum C1 And D Binding Domain Subunit (Hc) Vaccines Against C and D Neurotoxins, Robert P. Webb, Theresa J. Smith, Patrick M. Wright, Vicki A. Montgomery, Michael M. Meagher, and Leonard A. Smith

2006

PDF

Non-isothermal reaction-diffusion systems with thermodynamically coupled heat and mass transfer, Dr Y. Demirel

PDF

Purification and Scale-Up of a Recombinant Heavy Chain Fragment C of Botulinum Neurotoxin Serotype E in Pichia Pastoris GS115, Michael P. Dux, Rick Barent, Jayanta Sinha, Mark Gouthro, Todd Swanson, Ardis Barthuli, Mehmet Inan, John T. Ross, Leonard A. Smith, Theresa J. Smith, Robert Webb, Bonnie Loveless, Ian Henderson, and Michael M. Meagher

PDF

Phase stability analysis using interval Newton method with NRTL model, Dr. Hatice Gecegormez and Dr Y. Demirel

PDF

Sustainable Mining: Trends and Opportunities, James L. Hendrix

PDF

Solution chemistry control to make well defined submicron continuous fibres by electrospinning: the (CH3CH2CH2O)4Ti/AcOH/poly(N-vinylpyrrolidone) system, Dr.Gustavo Larsen and Dr.Maciej Skotak

PDF

Solution chemistry control to make well defined submicron continuous fibres by electrospinning: the (CH3CH2CH2O)4Ti/AcOH/poly(N-vinylpyrrolidone) system, Dr.Gustavo Larsen and Dr.Maciej Skotak

PDF

High-Resolution Thin-Film Device to Sense Texture by Touch, Vivek C. Maheshwari and Ravi Saraf