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2021

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Teaching Metabolism in Upper-Division Undergraduate Biochemistry Courses using Online Computational Systems and Dynamical Models Improves Student Performance, Christine S. Booth, Changsoo Song, Michelle E. Howell, Achilles Rasquinha, Aleš Saska, Resa M. Helikar, Sharmin M. Sikich, Brain A. Couch, Karin van Dijk, Rebecca Roston, and Tomáš Helikar

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A co-opted steroid synthesis gene, maintained in sorghum but not maize, is associated with a divergence in leaf wax chemistry, Lucas Busta, Elizabeth Schmitz, Dylan K. Kosma, James Schnable, and Edgar B. Cahoon

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Isoprene Production from Municipal Wastewater Biosolids by Engineered Archaeon Methanosarcina acetivorans, Sean Carr, Jared Aldridge, and Nicole R. Buan

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Long non-coding RNA Meg3 deficiency impairs glucose homeostasis and insulin signaling by inducing cellular senescence of hepatic endothelium in obesity, Xiao Cheng, Mohamed Sham Shihabudeen Haider Ali, Matthew Moran, Martonio Ponte Viana, Sarah L. Schlichte, Matthew C. Zimmerman, Oleh Khalimonchuk, Mark W. Feinberg, and Xinghui Sun

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The Need for Research-Grade Systems Modeling Technologies for Life Science Education, Tomáš Helikar

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Integrative computational approach identifies drug targets in CD4+ T-cell-mediated immune disorders, Bhanwar L. Puniya, Rada Amin, Bailee Lichter, Robert Moore, Alex Ciurej, Sydney J. Bennett, Ab Rauf Shah, Matteo Barberis, and Tomáš Helikar

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Structural basis for Clostridium perfringens enterotoxin targeting of claudins at tight junctions in mammalian gut, Alex J. Vecchio, Sewwandi S. Rathnayake, and Robert M. Stroud

2020

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Automated inference of Boolean models from molecular interaction maps using CaSQ, Sara Sadat Aghamiri, Vidisha Singh, Aurelien Naldi, Tomáš Helikar, Sylvain Soliman, and Anna Niarakis

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Integrated Unicellular/Filamentous Algal Production, Harvesting and Remediation System, Paul N. Black, James Allen, and Timothy J Nicodemus

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Insights from the Inclusive Environments and Metrics in Biology Education and Research Network: Our Experience Organizing Inclusive Biology Education Research Events, Rebecca A. Campbell-Montalvo, Natalia Caporale, Gary S. McDowell, Candice Idlebird, Katie M. Wiens, Kimberly M. Jackson, Jana D. Marcette, and Michael E. Moore

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Metabolic Feedback Inhibition Influences Metabolite Secretion by the Human Gut Symbiont Bacteroides thetaiotaomicron, Jennie L. Catlett, Jonathan Catazaro, Mikaela Cashman, Sean Carr, Robert Powers, Myra B. Cohen, and Nicole R. Buan

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Healthy pregnancies and essential fats: focus group discussions with Zambian women on dietary need and acceptability of a novel RUSF containing fish oil DHA, Catherine Chunda-Liyoka, Mwansa Ketty Lubeya, Mercy Imakando, Sophia Kisling, Sonoor Majid, Mary Willis, Charles Wood, Chipepo Kankasa, and Concetta C. DiRusso

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COMPOUNDS FOR INCREASING LIPID SYNTHESIS AND STORAGE, Concetta C. DiRusso and Nishikant Wase

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Role of the Hyaluronan Receptor, Stabilin-2/HARE, in Health and Disease, Edward N. Harris and Erika Baker

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Changes in lipid profiles of epileptic mouse mode, Alicia Johnson, Ryan A. Grove, Deepak Madhavan, Cory H.T. Boone, Camila Pereira Braga, Hannah Kyllo, Kaeli K. Samson, Kristina A. Simeone, Timothy A. Simeone, Tomáš Helikar, Corrine K. Hanson, and Jiri Adamec

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SBML Level 3: an extensible format for the exchange and reuse of biological models, Sarah M. Keating, Dagmar Waltemath, Tomáš Helikar, Michael Hucka, and 50 additional co-authors

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Sestrin2 Phosphorylation by ULK1 Induces Autophagic Degradation of Mitochondria Damaged by Copper-Induced Oxidative Stress, Heejeong Kim, Byeong Tak Jeon, Isaac M. Kim, Sydney Townsend, Carolyn M. Lorch, Martonio Viana, Jacob F. Myers, Caroline J. Trupp, Zachary T. Whipps, Mondira Kundu, Soonkyu Chung, Xinghui Sun, Oleh Khalimonchuk, Jaekwon Lee, and Seung-Hyun Ro

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Sestrins are evolutionarily conserved mediators of exercise benefits, Myungjin Kim, Alyson Sujkowski, Sim Namkoong, Bondong Gu, Tyler Cobb, Boyoung Kim, Allison H. Kowalsky, Chun-Seok Cho, Ian Semple, Seung-Hyun Ro, Carol Davis, Susan V. Brooks, Michael Karin, Robert J. Wessells, and Jun Hee Lee

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Validity of plasma collection cards for ferritin assessment—A proof-of-concept study, Karsten Koehler, Eileen Marks-Nelson, Camila Pereira Braga, Safiya E. Beckford, and Jiri Adamec

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Differences in Blood-derived Francisella tularensis Type B Strains from Clinical Cases of Tularemia, Marilyn A. Larson, Baha Abdalhamid, Bhanwar Lal Puniya, Tomáš Helikar, David W. Kelley, and Peter C. Iwen

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Genome biology of the paleotetraploid perennial biomass crop Miscanthus, Therese Mitros, Adam M. Session, Brandon T. James, Guohong Albert Wu, Katarzyna Glowacka, Kankshita Swaminathan, Daniel S. Rokhsar, and 35 additional co-authors

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Connecting Theory to Practice: Using Self-Determination Theory To Better Understand Inclusion in STEM, Michael E. Moore, Dulce M. Vega, Katie M. Wiens, and Natalia Caporale

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Transcriptome analysis-identified long noncoding RNA CRNDE in maintaining endothelial cell proliferation, migration, and tube formation, Matthew Moran, Xiao Cheng Zeng, Mohamed Sham Shihabudeen Haider Ali, Nishikant Wase, Nghi Nguyen, Weilong Yang, Chi Zhang, Concetta C. DiRusso, and Xinghui Sun

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A practical guide to mechanistic systems modeling in biology using a logic-based approach, Anna Niarakis and Tomáš Helikar

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Reactive Oxygen Species (ROS) mediated degradation of organophosphate T pesticides by the green microalgae Coccomyxa subellipsoidea☆, Timothy J Nicodemus, Concetta C. DiRusso, Mark A. Wilson, and Paul N. Black

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Training Population Optimization for Genomic Selection in Miscanthus, Marcus O. Olatoye, Lindsay V. Clark, Nicholas R. Labonte, Hongxu Dong, Maria S. Dwiyanti, Kossonou G. Anzoua, Joe E. Brummer, Bimal K. Ghimire, Elena Dzyubenko, Nikolay Dzyubenko, Larisa Bagmet, Andrey Sabitov, Pavel Chebukin, Katarzyna Głowacka, Kweon Heo, Xiaoli Jin, Hironori Nagano, Junhua Peng, Chang Y. Yu, Ji H. Yoo, Hua Zhao, Stephen P. Long, Toshihiko Yamada, Erik J. Sacks, and Alexander E. Lipka

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AMPHIPHILICCYCLOBUTENES AND CYLOBUTANES, Wantanee Sittiwong, Patrick H. Dussault, Raul Barletta, and Robert Power

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From Synthesis to Utilization: The Ins and Outs of Mitochondrial Heme, Samantha A. Swenson, Courtney M. Moore, Jason R. Marcero, Amy E. Medlock, Amit R. Reddi, and Oleh Khalimonchuk

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The genome evolution and domestication of tropical fruit mango, Peng Wang, Yingfeng Luo, Jianfeng Huang, Shenghan Gao, Guopeng Zhu, Zhiguo Dang, Jiangtao Gai, Meng Yang, Min Zhu, Huangkai Zhang, Xiuxu Ye, Aiping Gao, Xinyu Tan, Sen Wang, Shuangyang Wu, Edgar B. Cahoon, Beibei Bai, Zhichang Zhao, Qian Li, Junya Wei, Huarui Chen, Ruixiong Luo, Deyong Gong, Kexuan Tang, Bing Zhang, Zhangguang Ni, Guodi Huang, Songnian Hu, and Yeyuan Chen

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Systematic age-, organ-, and diet-associated ionome remodeling and the development of ionomic aging clocks, Bohan Zhang, Dmitriy I. Podolskiy, Marco Mariotti, Javier Seravalli, and Vadim N. Gladyshev

2019

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Arsenite exposure suppresses adipogenesis, mitochondrial biogenesis and thermogenesis via autophagy inhibition in brown adipose tissue, Jiyoung Bae, Yura Jang, Heejeong Kim, Kalika Mahato, cameron Schaecher, Issac M. Kim, Eunju Kim, and Seung-Hyun Ro

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An Arabidopsis protoplast isolation method reduces cytosolic acidification and activation of the chloroplast stress sensor SENSITIVE TO FREEZING 2, Allison C. Barnes, Christian G. Elowsky, and Rebecca Roston

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ACYLTRANSFERASES AND METHODS OF USING, Edgar Cahoon, Umidjon Iskandarov, Hae Jin Kim, and Jillian Collins-Silva

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Biomass yield in a genetically diverse Miscanthus sinensis germplasm panel evaluated at five locations revealed individuals with exceptional potential, Lindsay V. Clark, Maria S. Dwiyanti, Kossonou G. Anzoua, Joe E. Brummer, Bimal Kumar Ghimire, Katarzyna Glowacka, Megan Hall, Kweon Heo, Xiaoli Jin, Alexander E. Lipka, Junhua Peng, Toshihiko Yamada, Ji Hye Yoo, Chang Yeon Yu, Hua Zhao, Stephen P. Long, and Erik J. Sacks

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Genome‐wide association and genomic prediction for biomass yield in a genetically diverse Miscanthus sinensis germplasm panel phenotyped at five locations in Asia and North America, Lindsay V. Clark, Maria S. Dwiyanti, Kossonou G. Anzoua, Joe E. Brummer, Bimal Kumar Ghimire, Katarzyna Glowacka, Megan Hall, Kweon Heo, Xiaoli Jin, Alexander E. Lipka, Junhua Peng, Toshihiko Yamada, Ji Hye Yoo, Chang Yeon Yu, Hua Zhao, Stephen P. Long, and Erik J. Sacks

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Winter hardiness of Miscanthus (III): Genome‐wide association and genomic prediction for overwintering ability in Miscanthus sinensis, Hongxu Dong, Lindsay V. Clark, Alexander E. Lipka, Joe E. Brummer, Katarzyna Glowacka, Megan C. Hall, Kweon Heo, Xiaoli Jin, Junhua Peng, Toshihiko Yamada, Bimal Kumar Ghimire, Ji Hye Yoo, Chang Yeon Yu, Hua Zhao, Stephen P. Long, and Erik J. Sacks

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Ligand Binding and Signaling of HARE/Stabilin-2, Edward N. Harris and Fatima Cabral

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Reintegrating Biology Through the Nexus of Information and Energy, Kim L. Hoke, Sara L. Zimmer, Mary Jo Ondrechen, Amedee des Georges, Adam B. Roddy, Nicole R. Buan, and Craig E. Williamson

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Student Understanding of DNA Structure–Function Relationships Improves from Using 3D Learning Modules with Dynamic 3D Printed Models, Michelle E. Howell, Christine S. Booth, Sharmin M. Sikich, Tomáš Helikar, Rebecca Roston, Brain A. Couch, and Karin van Dijk

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Visualizing the Invisible: A Guide to Designing, Printing, and Incorporating Dynamic 3D Molecular Models to Teach Structure–Function Relationships, Michelle Howell, Karin van Dijk, Christine S. Booth, Tomáš Helikar, Brain A. Couch, and Rebecca Roston

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Comparison of montage with conventional stereoscopic seven‑field photographs for assessment of ETDRS diabetic retinopathy severity, Nam V. Nguyen, Erin M. Vigil, Muhammad Hassan, Muhammad S. Halim, Sean C. Baluyot, Hugo A. Guzman, Rubbia Afridi, Diana V. Do, and Yasir J. Sepah

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DNA Uptake by Type IV Filaments, Kurt H. Piepenbrink

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Downregulation of a CYP74 Rubber Particle Protein Increases Natural Rubber Production in Parthenium argentatum, Dante F. Placido, Niu Dong, Chen Dong, Von Mark V. Cruz, David A. Dierig, Rebecca E. Cahoon, Byung-guk Kang, Trinh Huynh, Maureen Whalen, Grisel Ponciano, and Colleen McMahan

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Chronic alcohol exposure alters circulating insulin and ghrelin levels: role of ghrelin in hepatic steatosis, Karuna Rasineni, Paul G. Thomes, Jacy L. Kubik, Edward N. Harris, Kusum K. Kharbanda, and Carol A. Casey

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The structure of PilA from Acinetobacter baumannii AB5075 suggests a mechanism for functional specialization in Acinetobacter type IV pili, Leslie A. Ronish, Erik Lillehoj, James K. Fields, Eric J. Sundberg, and Kurt Piepenbrink

Autophagy in Adipocyte Browning: Emerging Drug Target for Intervention in Obesity, Seung-Hyun Ro, Yura Jang, Jiyoung Bae, Isaac M. Kim, Cameron Schaecher, and Zachery D. Shomo

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Autophagy in Adipocyte Browning: Emerging Drug Target for Intervention in Obesity, Seung-Hyun Ro, Yura Jang, Jiyoung Bae, Isaac M. Kim, Cameron Schaecher, and Zachery D. Shomo

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The mitochondrial NAD+ transporter (NDT1) plays important roles in cellular NAD+ homeostasis in Arabidopsis thaliana, Izabel de Souza Chaves, Elias Feitosa-Araujo, Alexandra Florian, David B. Medeiros, Paula da Fonseca-Pereira, Lennart Charton, Elmien Heyneke, Jorge A. C. Apfata, Marcel V. Pires, Tabea Mettler-Altmann, Wagner L. Arajuo, H. Ekkehard Neuhaus, Ferdinando Palmieri, Toshihiro Obata, Andreas P. M. Weber, Nicole Linka, Alisdair R. Femie, and Adriano Nunes-Nesi

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High-Throughput Nano-Scale Characterization of Membrane Proteins Using Fluorescence-Detection Size-Exclusion Chromatography, Alex J. Vecchio and Robert M. Stroud

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Fatty acid transporter 2 reprograms neutrophils in cancer, Filippo Veglia; Vladimir A. Tyurin; Maria Blasi; Alessandra De Leo; Andrew Kossenkov; Laxminarasimha Donthireddy; To Tsun Ki Jerrick; Zach Schug; Subhasree Basu; Fang Wang; Emanuela Ricciotti; Concetta C. DiRusso; Maureen E. Murphy; Robert H. Vonderheide; Paul M. Lieberman; Charles Mulligan; Brian Nam; Neil Hockstein; Gregory Masters; Michael Guarino; Cindy Lin; Yulia Nefedova; Paul N. Black; Valerian E, Kagan; and Dmitry Gabrilovich

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Structural basis of non-canonical transcriptional regulation by the A-bound iron-sulfur protein WhiB1 in M. tuberculosis, Tao Wan, Shanren Li, Daisy Guiza Beltran, Andrew Schacht, Lu Zhang, Donald F. Becker, and Limei Zhang

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Remodeling of Chlamydomonas Metabolism Using Synthetic Inducers Results in Lipid Storage during Growth, Nishikant Wase, Boqiang Tu, Girish Kumar Rasineni, Ronald Cerny, Ryan Grove, Jiri Adamec, Paul N. Black, and Concetta DiRusso

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Charting a new frontier of science by integrating mathematical modeling to understand and predict complex biological systems, Katharine White, Kira McEntire, Nicole R. Buan, Kingshuk Ghosh, Lecia Robinson, and Elisar Barbar

2018

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Induction of oil accumulation by heat stress is metabolically distinct from N stress in the green microalgae Coccomyxa subellipsoidea C169, James W. Allen, Rahul Tevatia, Yaşar Demirel, Concetta C. DiRusso, and Paul N. Black

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Single-Molecule Unbinding Forces between the Polysaccharide Hyaluronan and Its Binding Proteins, Fouzia Bano, Markku I. Tammi, David W. Kang, Edward N. Harris, and Ralf P. Richter

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Towards the synthetic design of camelina oil enriched in tailored acetyl-triacylglycerols with medium-chain fatty acids, Sunil Bansal, Hae Jin Kim, GunNam Na, Megan E. Hamilton, Edgar B. Cahoon, Chaofu Lu, and Timothy P. Durrett

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Simulation of Stimulation: Cytokine Dosage and Cell Cycle Crosstalk Driving Timing-Dependent T Cell Differentiation, Matteo Barberis, Tomáš Helikar, and Paul Verbruggen

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Combining Mass Spectrometry and NMR Improves Metabolite Detection and Annotation, Fatema Bhinderwala, Nishikant Wase, Concetta DiRusso, and Robert Powers

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Reactive Oxygen Species in Chronic Obstructive Pulmonary Disease, Samia Boukhenouna, Mark A. Wilson, Karim Bahmed, and Beata Kosmider

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Methanogens: pushing the boundaries of biology, Nicole R. Buan

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Identification of Genes Encoding Enzymes Catalyzing the Early Steps of Carrot Polyacetylene Biosynthesis, Lucas Busta, Won Cheol Yim, Evan William LaBrant, Peng Wang, Lindsey Grimes, Kiah Malyszka, John C. Cushman, Patricia Santos, Dylan K. Kosma, and Edgar B. Cahoon

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Purification of Hepatocytes and Sinusoidal Endothelial Cells from Mouse Liver Perfusion, Fatima Cabral, Colton M. Miller, Katrina M. Kudrna, Blake E. Hass, Jocelyn G. Daubendiek, Brianna M. Kellar, and Edward N. Harris

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Total Mercury Determination in Muscle and Liver Tissue Samples from Brazilian Amazon Fish Using Slurry Sampling, João Vitor de Queiroz, José Cavalcante Souza Vieira, Izabela da Cunha Bataglioli, Alis Correia Bittarello, Camila Pereira Braga, Grasieli de Oliveira, Cilene do Carmo Federici Padilha, and Pedro de Magalhães Padilha

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Structural Determinants for the Interactions of Chemically Modified Nucleic Acids with the Stabilin‑2 Clearance Receptor, Hans Gaus, Colton M. Miller, Punit P. Seth, and Edward N. Harris

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Photosystem II Subunit S overexpression increases the efficiency of water use in a field-grown crop, Katarzyna Glowacka, Johannes Kromdijk, Katherine Kucera, Jiayang Xie, Amanda P. Cavanagh, Lauriebeth Leonelli, Andrew D. B. Leakey, Donald R. Ort, Krishna K. Niyogi, and Stephen P. Long

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Visualizing the Invisible: A Guide to Designing, Printing, and Incorporating Dynamic 3D Molecular Models to Teach Structure–Function Relationships, Michelle E. Howell, Karin V. van Dijk, Christine S. Booth, Tomáš Helikar, Brian A. Couch, and Rebecca Roston

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Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1, Tyler B. Johnson, Keegan Mechels, Ruth Ellen Anderson, Jacob T. Cain, David A. Sturdevant, Stephen Braddock, Hailey Pinz, Mark A. Wilson, Megan Landsverk, Kyle J. Roux, and Jill M. Weimer

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Dietary Omega-3 and Omega-6 Polyunsaturated Fatty Acids Modulate Hepatic Pathology, Saraswoti Khadge, J. Graham Sharp, Geoffrey M. Thiele, Timothy R. McGuire, Lynell W. Klassen, Michael J. Duryee, Holly C. Britton, Jordan Beck, Paul N. Black, Concetta DiRusso, and James Talmadge

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Long-Chain Omega-3 Polyunsaturated Fatty Acids Modulate Mammary Gland Composition and Inflammation, Saraswoti Khadge, Geoffrey M. Thiele, J. Graham Sharp, Timothy R. McGuire, Lynell W. Klassen, Paul N. Black, Concetta DiRusso, and James Talmadge

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Structural Basis for the Substrate Inhibition of Proline Utilization A by Proline, David A. Korasick, Travis A. Pemberton, Benjamin W. Arentson, Donald F. Becker, and John J. Tanner

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Lipid transport required to make lipids of photosynthetic membranes, Evan LaBrant, Allison C. Barnes, and Rebecca Roston

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REVERSIBLE HEPARIN MOLECULES AND METHODS OF MAKING AND USING THE SAME, Jian Liu, Yongmei Xu, Robert J. Linhardt, and Edward Harris

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Endosomal Escape of Antisense Oligonucleotides Internalized by Stabilin Receptors Is Regulated by Rab5C and EEA1 During Endosomal Maturation, Colton M. Miller, W. Brad Wan, Punit P. Seth, and Edward N. Harris

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3-O sulfation of heparin leads to hepatotropism and longer circulatory half-life, Colton M. Miller, Yongmei Xu, Katrina M. Kudrna, Blake E. Hass, Brianna M. Kellar, Andrew W. Egger, Jian Liu, and Edward N. Harris

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CancerDiscover: an integrative pipeline for cancer biomarker and cancer class prediction from high-throughput sequencing data, Akram Mohammed, Greyson Biegert, Jiri Adamec, and Tomáš Helikar

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The CoLoMoTo Interactive Notebook: Accessible and Reproducible Computational Analyses for Qualitative Biological Networks, Aurelien Naldi, Celine Hernandez, Nicolas Levy, Gautier Stoll, Pedro T. Monteiro, Claudine Chaouiya, Tomáš Helikar, Andrei Zinovyev, Laurence Calzone, Sarah Cohen-Boulakia, Denis Thieffry, and Loic Pauleve

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Identification of Biologically Essential Nodes via Determinative Power in Logical Models of Cellular Processes, Trevor Pentzien, Bhanwar L. Puniya, Tomas Helikar, and Mihaela T. Matache

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Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1, Elaine Pirie, Shayoni Ray, Calvin Pan, Wuxia Fu, Andrew F. Powers, Danielle Polikoff, Colton M. Miller, Katrina M. Kudrna, Edward N. Harris, Aldons J. Lusis, Rosanne M. Crooke, and Richard G. Lee

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A Mechanistic Computational Model Reveals That Plasticity of CD4+ T Cell Differentiation Is a Function of Cytokine Composition and Dosage, Bhanwar Lal Puniya, Robert G. Todd, Akram Mohammed, Deborah M. Brown, Matteo Barberis, and Tomáš Helikar

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Editorial: Structure and Function of Chloroplasts, Rebecca L. Roston, Juliette Jouhet, Fei Yu, and Hongbo Gao

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Intraperitoneal Nanotherapy for Metastatic Ovarian Cancer Based on siRNA-Mediated Suppression of DJ-1 Protein Combined with a Low Dose of Cisplatin, Canan Schumann, Stephanie Chan, Jess A. Miller, Yuliya Bortnyak, Katherine Carey, Alex Fedchyk, Leon Wong, Tetiana Korzun, Abraham S. Moses, Anna Lorenz, Delany Shea, Olena Taratula, Oleh Khalimonchuk, and Oleh Taratula

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LncRNA Meg3 protects endothelial function by regulating the DNA damage response, Mohamed Sham Shihabudeen Haider Ali, Xiao Cheng, Matthew Moran, Stefan Haemmig, Michael J. Naldrett, Sophie Alvarez, Mark W. Feinberg, and Xinghui Sun

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Computational Systems Biology Approach for the Study of Rheumatoid Arthritis: From a Molecular Map to a Dynamical Model, Vidisha Singh, Marek Ostaszewski, George D. Kalliolias, Gilles Chiocchia, Robert Olaso, Elisabeth Petit-Teixeira, Tomáš Helikar, and Anna Niarakis

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A TLR/AKT/FoxO3 immune tolerance–like pathway disrupts the repair capacity of oligodendrocyte progenitors, Taasin Srivastava, Parham Diba, Justin M. Dean, Fatima Banine, Daniel Shaver, Matthew Hagen, Xi Gong, Weiping Su, Ben Emery, Daniel L. Marks, Edward N. Harris, Bruce Baggentoss, Paul H. Weigel, Larry S. Sherman, and Stephen A. Back

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Adenosine has two faces: Regionally dichotomous adenosine tone in a model of epilepsy with comorbid sleep disorders, Ted J. Warren, Timothy A. Simeone, D. David Smith, Ryan Grove, Jiri Adamec, Kaeli K. Samson, Harrison M. Roundtree, Deepak Madhavan, and Kristina A. Simeone

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Role of Selenof as a Gatekeeper of Secreted Disulfide-Rich Glycoproteins, Sun Hee Yim, Robert A. Everley, Frank A. Schildberg, Sang-Goo Lee, Andrea Orsi, Zachary R. Barbati, Kutay Karatepe, Dmitry E. Fomenko, Petra A. Tsuji, Hongbo R. Luo, Steven P. Gygi, Roberto Sitia, Arlene H. Sharpe, Dolph L. Hatfield, and Vadim N. Gladyshev

2017

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Carbon and Acyl Chain Flux during Stress-induced Triglyceride Accumulation by Stable Isotopic Labeling of the Polar Microalga Coccomyxa subellipsoidea C169, James W. Allen, Concetta C. DiRusso, and Paul N. Black

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Quantification of Cell Signaling Networks Using Kinase Activity Chemosensors, Jon R. Beck, Edward N. Harris, and Cliff I. Stains

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Oxidative stress, metabolomics profiling, and mechanism of local anesthetic induced cell death in yeast, Cory Honsinger Thomas Boone, Ryan A. Grove, Dana Adamcova, Javier Seravalli, and Jiri Adamec

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BioSIMP: Using Software Testing Techniques for Sampling and Inference in Biological Organisms, Mikaela Cashman, Jennie L. Catlett, Myra B. Cohen, Nicole R. Buan, Zahmeeth Sakkaff, Massimiliano Pierobon, and Christine A. Kelley

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Toxoplasma DJ-1 Regulates Organelle Secretion by a Direct Interaction with Calcium-Dependent Protein Kinase 1, Matthew A. Child, Megan Garland, Ian Foe, Peter Madzelan, Moritz Treeck, Wouter A. van der Linden, Kristina Oresic Bender, Evanthie Weerapana, Mark A. Wilson, John C. Boothroyd, and Michael L. Reese

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Organ-specific regulation of ATP7A abundance is coordinated with systemic copper homeostasis, Haarin Chun, Tracy Catterson, Heejeong Kim, Jaekwon Lee, and Byung-Eun Kim

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Physiological Evidence for Isopotential Tunneling in the Electron Transport Chain of Methane-Producing Archaea, Nikolas Duszenko and Nicole R. Buan

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Significant enhancement of fatty acid composition in seeds of the allohexaploid, Camelina sativa, using CRISPR/Cas9 gene editing, Wen Zhi Jhang, Isabelle M. Henry, Peter G. Lynagh, Lucia Comai, Edgar B. Cahoon, and Donald P. Weeks

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Metalloproteases of the inner mitochondrial membrane, Roman M. Levytskyy, Iryna Bohovych, and Oleh Khalimonchuk

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Short Carboxylic Acid-Carboxylate Hydrogen Bonds Can Have Fully Localized Protons, Jiusheng Lin, Edwin Pozharski, and Mark A. Wilson

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Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2, Brandon L. Logeman, L. Kent Wood, Jaekwoon Lee, and Dennis J. Thiele

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Identification of potential tissue-specific cancer biomarkers and development of cancer versus normal genomic classifiers, Akram Mohammed, Greyson Biegert, Jiri Adamec, and Tomáš Helikar

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SECs (Sinusoidal Endothelial Cells), Liver Microenvironment, and Fibrosis, Vaishaali Natarajan, Edward N. Harris, and Srivatsan Kidambi

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Metabolic Investigations of the Molecular Mechanisms Associated with Parkinson’s Disease, Robert Powers, Shulei Lei, Annadurai Anandhan, Darrell D. Marshall, Bradley Worley, Ronald Cerny, Eric D. Dodds, Yuting Huang, Mihalis I. Panayiotidis, Aglaia Pappa, and Rodrigo Franco